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Marihuana pp 299-312 | Cite as

Inhibitory Effects of Δ9-Tetrahydrocannabinol on Nucleic Acid Synthesis and Proteins in Cultured Lymphocytes

  • Gabriel G. Nahas
  • Bernard Desoize
  • Joy Hsu
  • A. Morishima

Abstract

We have reported in other publications [16, 17] that two natural psychoactive cannabinoids, Δ8- and Δ9-tetrahydrocannibinol, their hydroxylated derivatives, and four nonpsychoactive cannabinoids: cannabinol, cannabidiol, cannabichromene, and cannabicyclol, inhibit in similar concentrations (10-5 Mto 10-4 M)blastogenesis of human lymphocytes. It was suggested that this inhibitory effect of the natural cannabinoids was induced in part by olivetol or 5n-amylresorcinol, which has the structure of the C ring of these compounds.

Keywords

Thymidine Incorporation Nucleic Acid Synthesis Macromolecular Synthesis Precursor Incorporation Mixed Leukocyte Culture 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag New York Inc. 1976

Authors and Affiliations

  • Gabriel G. Nahas
  • Bernard Desoize
  • Joy Hsu
  • A. Morishima

There are no affiliations available

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