Abstract
The B cell antigen receptor is a complex consisting of the membrane-bound immunoglobulin (mIg) molecule and two B cell-specific transmembrane proteins (Ig-α and Ig-β) which form a covalently linked α/β heterodimer (for review see Reth et al., 1991; Reth, 1992). All five different mIg classes are associated with the same α/β heterodimer (Venkitaraman et al., 1991) although, depending on the Ig class, the Ig-α molecule can differ in the glycosylation of its extracellular Ig domain (Campbell et al., 1991). The Ig-a and the Ig-β proteins both contain in their cytoplasmic tail a sequence motif (Reth 1989), which is important for their signaling function (for review see Cambier, 1992; Chan et al., 1992).
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© 1993 Springer-Verlag Berlin Heidelberg
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Alber, G., Flaswinkel, H., Kim, KM., Weiser, P., Reth, M. (1993). Structure and Function of the B Cell Antigen Receptors. In: Gergely, J., et al. Progress in Immunology Vol. VIII. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-51479-1_4
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DOI: https://doi.org/10.1007/978-3-642-51479-1_4
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