Hypercoagulative syndrome: Molecular markers for the identification of cardiovascular patients at risk

  • Hans Martin Hoffmeister
  • W. Heller
  • L. Seipel


In many cardiovascular diseases thromb-embolic events play a key role. Especially in patients with acute coronary syndromes a hypercoagulative state is known. Information, however, whether such alterations do exist prior to the clinical event is limited. Recent progress in the development of sensitive and specific tests to determine molecular markers of (re)activation of several pathways of the coagulation and of the fibrinolytic system is evident. The possible impact of such molecular markers for the identification of cardiovascular patients at risk as well as the meaning of such markers to prognosticate future cardiovascular events is summarized.

Key words

Molecular markers coagulation fibrinolysis inflammation tissue injury 


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Copyright information

© Dr. Dietrich Steinkopff Verlag GmbH & Co. KG, Darmstadt 2000

Authors and Affiliations

  • Hans Martin Hoffmeister
    • 1
  • W. Heller
    • 1
  • L. Seipel
    • 1
  1. 1.Abteilung Innere Medizin IIIMedizinische UniversitätsklinikTübingenGermany

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