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Role of Secretory Dense Granule Organelles in the Pathogenesis of Toxoplasmosis

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Toxoplasma gondii

Part of the book series: Current Topics in Microbiology and Immunology ((CT MICROBIOLOGY,volume 219))

Abstract

Multiplication of Toxoplasma gondii only occurs intracellularly inside a specialized compartment called the parasitophorous vacuole (PV). Regulated secretory processes are key to the success of the intracellular parasitism of Toxoplasma as the parasite extensively modifies the newly formed vacuole using secreted proteins (Beckers et al. 1994; Charif et al. 1990; Sibley and Krahenbuhl 1988). The main structural modification of the PV consists of elaboration of a network of tubular membranes that are continuous with the vacuolar membrane (Sibley and Krahenbuhl 1988; Sibley et al. 1986, 1995).

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© 1996 Springer-Verlag Berlin Heidelberg

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Cesbron-Delauw, MF., Lecordier, L., Mercier, C. (1996). Role of Secretory Dense Granule Organelles in the Pathogenesis of Toxoplasmosis. In: Gross, U. (eds) Toxoplasma gondii. Current Topics in Microbiology and Immunology, vol 219. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-51014-4_6

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  • DOI: https://doi.org/10.1007/978-3-642-51014-4_6

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-51016-8

  • Online ISBN: 978-3-642-51014-4

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