Abstract
Wound healing takes place through a series of events involving coagulation, inflammation, proliferative phenomena (fibroblasts, epithelial cells) neoangiogenesis, and the synthesis and depositing of new connective tissue (1,2). Collagen, which comprises over ten different types of macromolecules, represents a factor that modulates various phases in the healing process due to its interaction with cells and growth factors. In fact, it favors chemiotactic responses of monocytes and fibroblasts, epithelial differentiation and endothelial activity. In addition it replaces matter that is lost in injury (3)(4)-Science has long been familiar with several physical, chemical and biological agents that can stimulate or delay the healing process (3)(4). Among these, defocused and/or “low power” lasers are especially important since, given equal conditions, they can exert opposite, dosedependent effects (5,6,7,8,9,10,11,12). In turn, the laser dosage depends on the interrelationship between physical, biological and clinical factors. The significant physical factors include energetic density, power density, wavelength, type of emission (continuous or pulsing), the features of each pulse and the beam’s divergence and expansion.
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© 1992 Springer-Verlag Berlin Heidelberg
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Longo, L., Corcos, L. (1992). Defocused CO2 Laser Therapy in Pathologic Wound Healing. In: Waidelich, W., Waidelich, R., Hofstetter, A. (eds) Laser in der Medizin / Laser in Medicine. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-50234-7_102
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DOI: https://doi.org/10.1007/978-3-642-50234-7_102
Publisher Name: Springer, Berlin, Heidelberg
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