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Tumors and Tumorlike Lesions of Bone pp 485–503Cite as

Tumors Arising at Site of Preexisting Bone Lesions

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Abstract

The development of sarcoma is the most serious complication of Paget disease. In fact, Paget’s original case (1877) developed a fibrosarcoma in the radius after 22 years, and five of his 23 patients died of sarcoma. Although well recognized as a possible complication of Paget disease, the exact incidence of malignancy is difficult to establish because there is no reliable statistical information on the frequency of uncomplicated disease; in the world literature the reported incidence of malignancy ranges from 0.15% to 20%.

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Authors and Affiliations

  1. W.H.O. Collaborating Center for the Histological Definition and Classification of Bone Tumors, Sweden

    Fritz Schajowicz M.D. (Head, Professor of Pathology, Director of the Latin American Registry of Bone Pathology, Visiting Distinguished Professor)

  2. National University of Buenos Aires, Buenos Aires, Argentina

    Fritz Schajowicz M.D. (Head, Professor of Pathology, Director of the Latin American Registry of Bone Pathology, Visiting Distinguished Professor)

  3. Department of Orthopedic Surgery, St. Louis University Medical Center, St. Louis, Missouri, USA

    Fritz Schajowicz M.D. (Head, Professor of Pathology, Director of the Latin American Registry of Bone Pathology, Visiting Distinguished Professor)

  4. Rush-Presbyterian-St. Luke’s Medical Center, Chicago, Illinois, USA

    Fritz Schajowicz M.D. (Head, Professor of Pathology, Director of the Latin American Registry of Bone Pathology, Visiting Distinguished Professor)

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  1. Fritz Schajowicz M.D.
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© 1994 Springer-Verlag Berlin Heidelberg

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Schajowicz, F. (1994). Tumors Arising at Site of Preexisting Bone Lesions. In: Tumors and Tumorlike Lesions of Bone. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-49954-8_9

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  • DOI: https://doi.org/10.1007/978-3-642-49954-8_9

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