Vitamin D-ascorbic Acid Association in Bone Metabolism
Previous results (Thornton and Brownrigg, 1961) have indicated that ascorbic acid influenced the skeletal response of chicks to vitamin D3 deficiency. Turnover of skeletal 45Ca was enhanced in vitamin D3 deficient individuals in the presence of ascorbic acid, suggesting a change in the bone metabolic rate. No specific role for vitamin D in bone cells has been evolved; however, investigations with cartilage have suggested a metabolic function in that tissue. It appears to be needed for normal formation and metabolism of citric acid (Neuman and Neuman, 1958).
KeywordsAscorbic Acid Deficient Group Phosphate Release Calcium Utilization Phosphate Mobilization
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