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A Biomolecular Survey of Calcification

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Calcified Tissues 1965

Abstract

Deposits of inorganic calcium salts are so familiar to biologists that they seldom warrant close attention and are dismissed frequently as waste products. In spite of an increasing awareness that mineralization is a highly organized process, however, it is immediately apparent from the literature that we derive most of our ideas about the ultrastructural basis of calcification from studies of bone. There is little correlative data from other tissues containing calcium phosphate, and the few publications on the molecular structures associated with calcium carbonate in invertebrates are sufficient to emphasize the lack of information about the nature and genesis of the same salt in plants. The present grossly unbalanced state of knowledge is best illustrated by an appeal to mass. The investigations of calcium phosphate in vertebrates far exceed all other studies of calcium salts, yet bone, dentine and enamel are the least abundant mineralized tissues, constituting a fraction of a percent of the calcium oxalate in plants, where the nature of the inorganic substances present seems to have been neglected and where there appear to be no reports of the ultrastructure in the literature.

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Author information

Authors and Affiliations

  1. Astbury Department of Biophysics, Leeds University, Leeds, Yorksh., England

    F. G. E. Pautard

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  1. F. G. E. Pautard
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Editors and Affiliations

  1. Laboratorium für experimentelle Chirurgie, Schweizerisches Forschungsinstitut, Davos, Schweiz

    H. Fleisch

  2. School of Dental Surgery, Royal Dental Hospital, London, England

    H. J. J. Blackwood

  3. M.R.C. Bone-seeking Isotopes Research Unit, Churchill Hospital, Oxford, England

    M. Owen

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© 1966 Springer-Verlag Berlin Heidelberg

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Pautard, F.G.E. (1966). A Biomolecular Survey of Calcification. In: Fleisch, H., Blackwood, H.J.J., Owen, M. (eds) Calcified Tissues 1965. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-49802-2_22

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  • DOI: https://doi.org/10.1007/978-3-642-49802-2_22

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-49514-4

  • Online ISBN: 978-3-642-49802-2

  • eBook Packages: Springer Book Archive

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