The Significance of the Carrier Effect for the Induction of Antibodies

Rajewsky, K.

doi:10.1007/978-3-642-49733-9_9

The Significance of the Carrier Effect for the Induction of Antibodies

K. Rajewsky⁵

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Abstract

When an immunogen is injected into a higher organism, antibodies reacting specifically with that immunogen are produced. Since a vast number of antibody specificities exist, and since cogent evidence indicates that antibody specificity is determined by the primary structure of the antibody polypeptide chains, the question has to be asked of how antigen induces the structural genes coding for the “right” antibodies, and only these, to initiate protein synthesis.

Keywords

Antigenic Determinant
Foetal Liver Cell
Antibody Induction
Immunoglobulin Receptor
Carrier Effect

These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Authors and Affiliations

Institut für Genetik der Universität, 5 Köln-Lindenthal, Weyertal 121, Deutschland
Prof. Dr. K. Rajewsky

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Prof. Dr. K. Rajewsky
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Editors and Affiliations

Direktor, Max-Planck-Instituts für Immunbiologie, 7800, Freiburg-Zähringen, Deutschland
Professor Dr. Otto Westphal
Direktor der Medizinischen Klinik der Universität, 7400, Tübingen, Deutschland
Professor Dr. Dr. h. c. Hans-Erhard Bock
Vorstand des Instituts für experimentelle Pathologie, Farbenfabriken Bayer AG, 5600, Wuppertal-Elberfeld, Deutschland
Professor Dr. Ekkehard Grundmann

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Rajewsky, K. (1969). The Significance of the Carrier Effect for the Induction of Antibodies. In: Westphal, O., Bock, HE., Grundmann, E. (eds) Current Problems in Immunology. Bayer-Symposium, vol 1. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-49733-9_9

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DOI: https://doi.org/10.1007/978-3-642-49733-9_9
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-49454-3
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