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Destruction of Complement-Target Cell Complexes by Mononuclear Leukocytes

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Abstract

There are two primary mechanisms by which biological membranes may sustain irreversible damage in the course of immune reactions, one involving lymphocytes, the other humoral factors. Damage of membranes by sensitized mononuclear cells usually does not require participation of serum factors such as complement; and membrane damage by antibody and complement occurs without participation of cells.

Keywords

  • Target Cell
  • Fetal Calf Serum
  • Membrane Damage
  • Polymorphonuclear Leukocyte
  • Sheep Erythrocyte

These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

This is publication number 324 from the Department of Experimental Pathology, Scripps Clinic and Research Foundation, La Jolla, California.

This work was supported by United States Public Health Service Grant AI-07007, American Heart Association, Inc. Grant 68–666 and United States Atomic Energy Commission Contract AT (04–3)−730.

Dr Manni is supported by United States Public Health Service Training Grant No. 5TIGM683.

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Müller-Eberhard, H.J., Perlmann, P., Perlmann, H., Manni, J.A. (1969). Destruction of Complement-Target Cell Complexes by Mononuclear Leukocytes. In: Westphal, O., Bock, HE., Grundmann, E. (eds) Current Problems in Immunology. Bayer-Symposium, vol 1. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-49733-9_2

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  • DOI: https://doi.org/10.1007/978-3-642-49733-9_2

  • Publisher Name: Springer, Berlin, Heidelberg

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