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The in Vitro Transformation of Lymphocytes of Premature and Mature Infants

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Part of the Bayer-Symposium book series (BAYER-SYMP,volume 1)

Abstract

The functions of organs in newborn infants are immature according to Salge [8]. He was speaking of “developing functions,” a notion that has prompted a great number of studies. Oftentimes the newborn is thought helpless. From the neurological point of view and that of behavioral research this view has first been vigorously attacked by Peiper [7]. Decisive progress has been made in immunology during recent years, suggesting that the newborn infant is not helpless as regards also his resistance. This does not apply so much to the transplacental transmission of immune antibodies as to the fact that the fetus is able to form antibodies upon stimulation by antigens while still in the uterus. IgM-globulin was thus demonstrated following intrauterine inoculation with syphilis or toxoplasmosis and found to be of diagnostic value as in the case of the FTA-absorption test.

Keywords

  • Premature Infant
  • Newborn Infant
  • Immunological System
  • Premature Newborn
  • Mature Infant

These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

The experimental studies were supported by a grant of the “Deutsche Forschungsgemeinschaft”, which is also hereby gratefully acknowledged.

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References

  1. Brody, J. I., F. A. Oski, and E. E. Wallach: Lancet 1968 I, 1396.

    Google Scholar 

  2. Gropp, A., u. R. Fischer: Kiln. Wschr. 44, 665 (1966).

    CrossRef  CAS  Google Scholar 

  3. Lindahl-Kiessling, K., and J. A. Böök: Lancet 1964 I, 591.

    Google Scholar 

  4. Nowell, P. C.: Cancer Res. 20, 462 (1960).

    PubMed  CAS  Google Scholar 

  5. Oehme, J.: In: Fortschritte der Pädologie. Berlin-Heidelberg-New York: Springer 1965.

    Google Scholar 

  6. Oehme, J.: Machr. Kinderheilk. 115, 148 (1967).

    CAS  Google Scholar 

  7. Peiper, A.: Med. Welt 19, 307 (1968).

    Google Scholar 

  8. Salge, B. Z.: Kinderheilk. 4, 171 (1912) und 5, 11 (1913).

    Google Scholar 

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© 1969 Springer-Veralg Berlin · Heidelberg

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Oehme, J. (1969). The in Vitro Transformation of Lymphocytes of Premature and Mature Infants. In: Westphal, O., Bock, HE., Grundmann, E. (eds) Current Problems in Immunology. Bayer-Symposium, vol 1. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-49733-9_15

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  • DOI: https://doi.org/10.1007/978-3-642-49733-9_15

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-49454-3

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