Abstract
Following the work of Rosenberg et al. [1] and Rosenberg and Van Camp [2] extensive trials of cis-Platinum Diamminedichloride (PDD) in tumor bearing animals were undertaken by Speer et al. in our laboratories. Based on these animal studies clinical trials were started in April, 1971. The results observed in twelve patients receiving PDD were presented in Prague in August of the same year. Marked tumor regression was noted in several patients and observations on tissue distribution as well as pertinent information on dosage levels and schedules were obtained.
Keywords
- Squamous Cell Carcinoma
- Versus Versus Versus
- Acute Myelogenous Leukemia
- Versus Versus Versus Versus
- Versus Versus Versus Versus Versus
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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References
Rosenberg, B., Van Camp, L., Trosko, J. E., Mansour, V. H.: Platinum compounds: a new class of potent anti-tumour agents. Nature (Lond.) 222, 385 (1969).
Rosenberg, B., Van Camp, L.: The successful regression of large solid sarcoma 180 tumors by platinum compounds. Cancer Res. 30, 1799 (1970).
Speer, R. J., Lapis, S., Ridgway, H., Meyers, T. D., Hill, J. M.: Cis-platinous diamminodichloride (PDD) in combination chemotherapy of leukaemia L1210. Proceedings of the VII International Congress of Chemotherapy, Prague 1971. Special print of Adv. in Microbial and Anti-neoplastic Chemotherapy 1973.
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© 1974 Springer-Verlag Berlin · Heidelberg
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Hill, J.M., Loeb, E., MacLellan, A.S., Hill, N.O., Khan, A., Kogler, J. (1974). Further Clinical Experience with cis-Platinum (II) Diamminedichloride. In: Connors, T.A., Roberts, J.J. (eds) Platinum Coordination Complexes in Cancer Chemotherapy. Recent Results in Cancer Research, vol 48. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-49306-5_10
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DOI: https://doi.org/10.1007/978-3-642-49306-5_10
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-49308-9
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