Abstract
It is well known that the methods currently being used in successful drug development are very expensive, involving a large number of carefully monitored clinical trials and provide the results only after a long period of time. Even when a standardized registration procedure is followed, however, it does not necessarily guarantee that the medication will become available on the market. This may be due in part to the pharmaceutical industry which, in addition to fulfilling its usual requirements in establishing sufficient proof of the efficacy and safety of a new drug to the regulatory authorities as well as to the health insurances, also often has to substantiate the drugs economic efficiency.
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References
Arzneimittel-Kompendium der Schweiz 1989. Documed AG, Basel, 1989
Economics of ceftriaxone use. Editiones <Roche>, Basle, 1987
Fernex, M., Havas, L., Ryff, J.C., Clarke, M.R.: Ergebnisse der klinischen Prüfung von Ceftriaxon. Hahnenklee-Symposium, Basel 1981: Editiones <Roche>, 1982, pp. 389–415
International Classification of Diseases, 9th Revision, U.S. Departement of Health and Human Services, DHHS Publication No. (PHS) 80–1260
Prognos-Beiträge zur Unternehmungsführung. Simulation als Instrument der Planung in Wirtschaft und Verwaltung. Verlag moderne Industrie, Zürich, 1973
Schweizer Spital, 52. Jahrgang Heft 11, 1988
Schweizerischer Diagnose Index. Institut für medizinische Information und Statistik (IMS), Zug, 1988
Spezialitäten-Liste. Bundesamt für Sozialversicherung (BSV), Bern, März 1989
VESKA Medizinische Statistik. Gesamtstatistik 1987 Diagnosen und Operationen Vereinigung Schweizerischer Krankenhäuser (VESKA), Aarau, 1988; pp 55–61
Doubilet, P., Begg, C.B., Weinstein, M.C., Braun, P., McNeil, B.J.: Probabilistic Sensitivity Analysis Using Monte Carlo Simulation. A Practical Approach. Medical Decision Making 1985, Vol.5, No.2, pp 157–177
SMLTREE: computer program for decision analysis and Monte Carlo Simulation Jim Hollenberg, 445 E 68th St, BOX 20, New York, NY 10021, USA
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© 1992 Springer-Verlag Berlin Heidelberg
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Bergemann, R., Brandt, A., Nawrath, T., Richter, A., Siegrist, W., Sorenson, F. (1992). Computer Aided Simulation Analysis (Casa) in Order to Test Cost-Effectiveness of Drugs Using the Example of Ceftriaxone (RocephinR). In: Jöckel, KH., Rothe, G., Sendler, W. (eds) Bootstrapping and Related Techniques. Lecture Notes in Economics and Mathematical Systems, vol 376. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-48850-4_28
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DOI: https://doi.org/10.1007/978-3-642-48850-4_28
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