Abstract
Transplant-related mortality (TRM) associated with acute graft-versus-host disease (aGvHD) and endothelial complications is still a major problem in human allogeneic bone marrow transplantation (BMT). While the role of donor T cell activation in aGvHD has been confirmed by experimental and clinical studies [1], there is increasing evidence for additional involvement of cytokines, predominantly tumor necrosis factor alpha (TNFα), in aGvHD and transplantrelated complications [2, 3].
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© 1992 Springer-Verlag, Berlin Heidelberg
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Holler, E. et al. (1992). Systemic Release of Tumor Necrosis Factor Alpha in Human Allogeneic Bone Marrow Transplantation: Clinical Risk Factors, Prognostic Significance, and Therapeutic Approaches. In: Freund, M., Link, H., Schmidt, R.E., Welte, K. (eds) Cytokines in Hemopoiesis, Oncology, and AIDS II. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-48715-6_54
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DOI: https://doi.org/10.1007/978-3-642-48715-6_54
Publisher Name: Springer, Berlin, Heidelberg
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