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Liposome Production: The Ethanol Injection Technique and the Development of the First Approved Liposome Dermatic

  • Conference paper
Liposome Dermatics

Part of the book series: Griesbach Conference ((GRIESBACH))

Abstract

In 1984, the CILAG company initiated the practical development of a liposome dermatic containing 1% of the antifungal econazole. Driven by the hypothesis that liposomally entrapped econazole might have beneficial clinical properties, focus was first directed towards finding a manufacturing technique with the potential for economic scale-up.

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References

  1. Batzri S, Korn ED (1973) Single bilayer liposomes prepared without sonication. Biochim Biophys Acta 298:1015–1019

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© 1992 Springer-Verlag Berlin Heidelberg

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Kriftner, R.W. (1992). Liposome Production: The Ethanol Injection Technique and the Development of the First Approved Liposome Dermatic. In: Braun-Falco, O., Korting, H.C., Maibach, H.I. (eds) Liposome Dermatics. Griesbach Conference. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-48391-2_10

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  • DOI: https://doi.org/10.1007/978-3-642-48391-2_10

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-55646-6

  • Online ISBN: 978-3-642-48391-2

  • eBook Packages: Springer Book Archive

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