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The First Description of the Symptoms of Experimental Pancreatic Diabetes by the Swiss Johann Conrad Brunner (1653–1727)

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Diabetes Its Medical and Cultural History

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Abstract

In 1889, by extirpating the pancreas in dogs, Mering and Min-kowski produced conclusive evidence as to the role of the pancreas in diabetogenesis. But 200 years before them, Johann Conrad Brunner, a Swiss physician and research-worker, in the context of a quite different problem, had likewise removed the dog’s pancreas. In describing the behavior of his experimental animals, he listed a series of important symptoms without suspecting what it was that he had discovered: namely, the clinical features of experimental diabetes; through his experiments, Brunner, even if unconsciously, was the true discoverer of this experimental form of pancreatic diabetes.

This work was carried out at the suggestion and under the guidance og Prof. Dr. med. et phil. G. Wolf-Heidegger.

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Authors
  1. Ole Christian Zimmermann
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Editors and Affiliations

  1. Institut für Medizin-und Wissenschaftsgeschichte, Medizinische Universität zu Lübeck, Ratzeburger Allee 160, 2400, Lübeck, Germany

    Dietrich von Engelhardt

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Zimmermann, O.C. (1989). The First Description of the Symptoms of Experimental Pancreatic Diabetes by the Swiss Johann Conrad Brunner (1653–1727). In: von Engelhardt, D. (eds) Diabetes Its Medical and Cultural History. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-48364-6_14

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  • DOI: https://doi.org/10.1007/978-3-642-48364-6_14

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-48366-0

  • Online ISBN: 978-3-642-48364-6

  • eBook Packages: Springer Book Archive

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