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Pharmakotherapie des myoklonisch-astatischen Petit mal und des Lennox-Syndroms

  • Conference paper
Book cover Aktuelle Neuropädiatrie 1986

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Zusammenfassung

Das myoklonisch-astatische Petit mal und das Lennox-Syndrom sind frühkindliche Anfallssyndrome, die oft nicht eindeutig voneinander abgegrenzt werden und eine besonders ungünstige Therapie- und Entwicklungsprognose haben.

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Literatur

  • Aicardi J (1986) Epilepsy in children. The international review of child neurology. Raven Press, New York

    Google Scholar 

  • Beaumanoir A (1985) The Lennox-Gastaut syndrome. In: Roger J, Dravet C, Bureau M, Dreyfuss FE, Wolf P (eds) Epileptic syndromes in infancy, childhood and adolescence. John Libby Eurotext, London Paris, pp 89–99

    Google Scholar 

  • Bensch J, Blennow H, Ferngren H, Gamstorp I (1977) A double-blind study of clonazepam in the treatment of therapyresistent epilepsy. Dev Med Child Neurol 19: 335–342

    Article  PubMed  CAS  Google Scholar 

  • Covanis A, Gupta AK, Jeavons PM (1982) Sodium valproate: monotherapy and polytherapy. Epilepsia 23: 693–720

    Article  PubMed  CAS  Google Scholar 

  • Doose H (1985) Myoclonic-astatic epilepsy of early childhood. In: Roger J, Dravet C, Bureau M, Dreyfuss FE, Wolf P (eds) Epileptic syndromes in infancy, childhood and adolescence. John Libby Eurotext, London Paris, pp 78–88

    Google Scholar 

  • Doose H, Völzke E (1979) Petit mal status in early childhood and dementia. Neuropediatrics 10: 10–14

    Article  CAS  Google Scholar 

  • Gastaut H (1981) The effect of benzodiazepines on chronic epilepsy in man. In: Hindmarch I, Stonier PD (eds) The Royal Society of Medicine international congress and symposium, series no. 43 “clobazam”. Academic Press, London, pp 141–149

    Google Scholar 

  • Gram L, Flachs H, Wurtz-Jorgensen A, Parnas J, Andersen B (1979) Sodium valproate, serum level and clinical effect: a controlled study. Epilepsia 20: 303–311

    Article  PubMed  CAS  Google Scholar 

  • Gram L, Drachman-Bentsen K, Parnas J, Flachs H (1982) Controlled trials in epilepsy: a review. Epilepsia 23: 491–519

    Article  PubMed  CAS  Google Scholar 

  • Greenblatt DJ, Shader RI, Abernathy DR (1983) Current status of benzodiazepines. New Engl J Med 309/I: 354–358, 11: 410–415

    Google Scholar 

  • Hansson O, Olsson I (1983) Minidose benzodiazepine in antiepileptic treatment. EFCNS Symposium Noordwijkerhout

    Google Scholar 

  • Henriksen O, Johannessen I (1980) Clinical observations of sodium valproate in children: an evaluation of therapeutic serum levels. In: Johannessen SI, Morselli PL, Pippenger CE, Richens A, Schmidt D, Meinardi H (eds) Antiepileptic therapy: advances in drug monitoring. Raven Press, New York, pp 253–261

    Google Scholar 

  • Herrantz JL, Arteaga R, Armijo JR (1982) Side effects of sodium valproate in monotherapy controlled by plasma levels: A study in 88 pediatric patients. Epilepsia 23: 203–214

    Article  Google Scholar 

  • Ishikawa A, Sakuma N, Nagashima T, Kohsaka S, Kajii N (1985) Clonazepam monotherapy for epilepsy in childhood. Brain Dev 7: 610–613

    PubMed  CAS  Google Scholar 

  • Janz D (1978) Über Pharmakoresistenz in der Epilepsiebehandlung. Dtsch Med Wochenschr 103: 1612–1619

    Article  PubMed  CAS  Google Scholar 

  • Jeavons PM (1984) Non-dose-related side effects of valproate. Epilepsia [Suppl] 25: 50–55

    Article  Google Scholar 

  • Killian J, Fromm GH (1970) A double-blind comparison of nitrazepam versus diazepam in myoclonic seizure disorders. Dev Med Child Neurol 13: 32–39

    Article  Google Scholar 

  • Lagenstein I, Willig RP, Iffland E (1979) Behandlung frühkindlicher Anfälle mit ACTH und Dexamethason unter standardisierten Bedingungen. Monatsschr Kinderheilkd 126: 492–499

    Google Scholar 

  • Mikkelsen B, Birket-Smith E, Brandt S et al. (1976) Clonazepam in the treatment of epilepsy. Arch Neurol 33: 322–325

    Article  PubMed  CAS  Google Scholar 

  • Morre M, Keane P, Vernieres J, Simiand J, Roncucci R (1984) Valproate: recent findings and perspectives. Epilepsia [Suppl] 25: 5–9

    Article  CAS  Google Scholar 

  • Nolte R (1979) Das Lennox-Gastaut Syndrom (Literaturübersicht). Klinisches Bild, Prognose, Therapie. In: Doose H, Kruse R, Lipinski C, Scheffner D, Weinmann HM (Hrsg) Beiträge zur Klassifikation und medikamentösen Therapie epileptischer Anfälle. Desitin Werke Karl Klinke GmbH, Hamburg, P 189–207

    Google Scholar 

  • Nolte R (1981) Myoklonisch-astatische Anfälle. Symptomatologie, Verlaufsgestalten und Prognose. Aktuelle Neuropädiatrie 2: 220–240

    Google Scholar 

  • Ohtahara S, Yamatogi Y, Ohtsuka Y (1976) Prognosis of the Lennox-Syndrome — longterm clinical and EEG follow-up study, especially with special reference relationship with the West syndrome. Fol Psychiatr Neurol Japon 30: 275–287

    CAS  Google Scholar 

  • Péchadre JC, Beudin P, Devoize J, Gibert J (1981) Utilisation du Clobazam comme antiépileptique dans le syndrome de Lennox et Gastaut. Encéphale 7: 181–190

    PubMed  Google Scholar 

  • Roussounis SH, Rudolf N (1977) Clonazepam in the treatment of children with intractable seizures. Dev Med Child Neurol 19: 326–334

    Article  PubMed  CAS  Google Scholar 

  • Scheffner D (1986) Fatal liver failure in children on valproate. Lancet 11: 511

    Article  Google Scholar 

  • Suzuki M, Maruyama H, Ishibashi Y et al. (1972) A Double-blind comparatice trial of sodiumdipropylacetate and ethosuximide in epilepsy in children with special emphasis on pure petitmal seizures. Medical Progr 82: 470–488

    Google Scholar 

  • Vasella F, Rüdeberg A, Da Silva V, Pavlincova E (1978) Doppelblinduntersuchung über die antikonvulsive Wirkung von Phenobarbital and Valproat beim Lennox-Syndrom. Schweiz Med Wochenschr 108: 713–716

    Google Scholar 

  • Vining EPG, Botsford E, Freeman J (1979) Valproat sodium in refractory seizures. Am J Dis Child 133: 274–276

    PubMed  CAS  Google Scholar 

  • Yamatogi Y, Ohsuka Y, Ishida T et al. (1979) Treatment of the Lennox syndrome with ACTH. A clinical and EEG study. Brain Dev 1 /4: 267–276

    Article  PubMed  CAS  Google Scholar 

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Authors
  1. R. Nolte
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Editor information

Editors and Affiliations

  1. Universitäts-Kinderklinik, Adenauerallee 119, 5300, Bonn 1, Deutschland

    Helmut Fichsel

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© 1987 Springer-Verlag Berlin Heidelberg

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Nolte, R. (1987). Pharmakotherapie des myoklonisch-astatischen Petit mal und des Lennox-Syndroms. In: Fichsel, H. (eds) Aktuelle Neuropädiatrie 1986. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-47569-6_24

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  • DOI: https://doi.org/10.1007/978-3-642-47569-6_24

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-47571-9

  • Online ISBN: 978-3-642-47569-6

  • eBook Packages: Springer Book Archive

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