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Outstanding Issues in Neuropathology and Neurochemistry of Schizophrenia

  • Conference paper
Search for the Causes of Schizophrenia

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Abstract

The four presentations in this section eloquently highlighted some of the new approaches and trends in studies of neurochemistry and neuropathology in schizophrenia over the last five years. The main features have been:

  • Pervasive use of in situ neurochemistry — the visualisation and quantitation of neurochemical parameters in brain sections.

  • Increasing use of high-resolution techniques permitting the visualisation of neurochemistry and molecular mechanisms within individual cellular elements. This has the great promise of identifying aberrant connectivity and circuitry.

  • Spreading use of cytoarchitectural and stereological methods to gain accurate estimates of cell density and number.

  • The establishment of the Stanley Foundation collection of brains from patients with schizophrenia, controls, depressives and bipolars. This offers major prospects for replication by different laboratories and integration of findings in the same set of brains.

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Authors and Affiliations

  1. Neuroscience and Psychiatry Unit, Stopford Building, Oxford Road, Manchester, UK

    J. F. W. Deakin

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  1. J. F. W. Deakin
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Editors and Affiliations

  1. Department of Psychiatry Faculty of Medicine, University of São Paulo, P.O. Box 3671, 05403-010, São Paul, SP, Brazil

    Wagner F. Gattaz M.D. (Professor and Chairman) (Professor and Chairman)

  2. University of Heidelberg, Germany

    Heinz Häfner (Prof. em. of Psychiatry, Director em., Head) (Prof. em. of Psychiatry, Director em., Head)

  3. Central Institute of Mental Health, Germany

    Heinz Häfner (Prof. em. of Psychiatry, Director em., Head) (Prof. em. of Psychiatry, Director em., Head)

  4. Schizophrenia Research Unit, P.O.Box 122 120, 68072, Mannheim, Germany

    Heinz Häfner (Prof. em. of Psychiatry, Director em., Head) (Prof. em. of Psychiatry, Director em., Head)

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© 1999 Dr. Dietrich Steinkopff Verlag GmbH & Co. KG, Darmstadt

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Deakin, J.F.W. (1999). Outstanding Issues in Neuropathology and Neurochemistry of Schizophrenia. In: Gattaz, W.F., Häfner, H. (eds) Search for the Causes of Schizophrenia. Steinkopff. https://doi.org/10.1007/978-3-642-47076-9_20

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  • DOI: https://doi.org/10.1007/978-3-642-47076-9_20

  • Publisher Name: Steinkopff

  • Print ISBN: 978-3-642-47078-3

  • Online ISBN: 978-3-642-47076-9

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