Abstract
DNA vaccines have several advantages over conventional vaccines, such as ease of construction, low expense for mass production, high temperature stability, and ability to induce a full spectrum of exceptionally long-lasting immune responses, including cytolytic T lymphocytes (CTL) [6, 13]. Furthermore, because the transgene antigen is synthesized by cells of the host animal, it may be processed for immune recognition via a protein degradation pathway that is distinct from that of exogenous protein antigen.
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© 1998 Springer-Verlag Berlin Heidelberg
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Wu, Y., Kipps, T.J. (1998). DNA vaccines with rapid intracellular degradation are more effective for inducing CTL. In: Raz, E. (eds) Gene Vaccination: Theory and Practice. Principles and Practice. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-46867-4_6
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DOI: https://doi.org/10.1007/978-3-642-46867-4_6
Publisher Name: Springer, Berlin, Heidelberg
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