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Multiple Alignment of Protein Sequences and Construction of Evolutionary Trees based on Amino Acid Properties — an Algebraic Approach

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Information Systems and Data Analysis
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Summary

This paper presents an essentially new method to construct phylogenetic trees from related amino acid sequences. The method is based on a new distance measure which describes sequence relationships by means of typical steric and physicochemical properties of the amino acids and is advantageous in some essential points. In particular, it avoids negative branches. The method was applied to different sets of protein sequences and the results compared with other well-established methods.

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© 1994 Springer-Verlag Berlin · Heidelberg

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Schmidt, W. (1994). Multiple Alignment of Protein Sequences and Construction of Evolutionary Trees based on Amino Acid Properties — an Algebraic Approach. In: Bock, HH., Lenski, W., Richter, M.M. (eds) Information Systems and Data Analysis. Studies in Classification, Data Analysis, and Knowledge Organization. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-46808-7_34

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  • DOI: https://doi.org/10.1007/978-3-642-46808-7_34

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-58057-7

  • Online ISBN: 978-3-642-46808-7

  • eBook Packages: Springer Book Archive

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