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The Role of Long Periods of Infectiousness in the Dynamics of Acquired Immunodeficiency Syndrome (AIDS)

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Part of the book series: Lecture Notes in Biomathematics ((LNBM,volume 81))

Abstract

Single and multiple group models for the spread of HIV (human immunodeficiency virus) are introduced. Partial analytical results for these models are presented for two specific cases. First for a model for which the duration of infectiousness has a negative exponential distribution and second for a model for which all individuals remain infectious for a fixed length of time.

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References

  1. Barré-Sinoussi, F., J. -C. Chermann, F. Rey, M. T. Nugeyre, S. Chamaret, J. Gruest, C. Dauguet, C. Axler-Blin, F. Brun-Vézinet, C. Rouzioux, W. Rozenbaum and L. Montagnier. Isolation of a T-lymphotropic retrovirus from a patient at risk for acquired immune deficiency syndrome (AIDS). Science 220: 868–70 (1983).

    Article  Google Scholar 

  2. Gallo, R.C., S. Z. Salahuddin, M. Popovic, G. M. Shearer, M. Kaplan, B. F. Haynes, T. J. Palker, R. Redfield, J. Oleske, B. Safai, G. White, P. Foster and P. D. Markhamet. Frequent detection and isolation of sytopathic retroviruses (HTLV-III) from patients with AIDS and at risk for AIDS. Science 224: 500–503 (1984).

    Article  Google Scholar 

  3. Gallo, R. C. The first human retrovirus. Scientific American 255: 88–98 (1986).

    Article  Google Scholar 

  4. Gallo, R.C. The AIDS virus. Scientific American 256: 47–56 (1987).

    Article  Google Scholar 

  5. Wong-Staal, F. and R. C. Gallo. Human T-Iymphotropic retroviruses. Nature 317: 1985: 395–403.

    Article  Google Scholar 

  6. Francis, D.F., P. M. Feorino, J. R. Broderson, H. M. McClure, J. P. Getchell, C. R. McGrath, B. Swenson, J. S. McDougal, E. L. Palmer, A. K. Harrison, F. BarreSinoussi, J. -C. Chermann, L. Montagnier, J. W. Curran, C. D. Cabradilla and V. S. Kalyanaraman. Infection of chimpanzees with lymphadenopathy-associated virus. Lancet 2: 1276–77 (1984).

    Article  Google Scholar 

  7. Salahuddin, S.Z., J. E. Groopman, P.D. Markham, M. G. Sarngaharan, R. R. Redfield, M. F. McLane, M. Essex, A. Sliski and R. C. Gallo. HTLV-III in symptom-free seronegative persons. Lancet 2: 1418–20 (1984).

    Article  Google Scholar 

  8. Lange, J. M. A., D. A. Paul, H. G. H.isman, et. al. Persistent HIV antigenaemia and decline of HIV core antibodies associated with transition to AIDS. Brit. Med. J. 293, 1986: 1459–62.

    Article  Google Scholar 

  9. Medley, G. F., R. M. Anderson, D. R. Cox, and L. Billard. Incubation period of AIDS in patients infected via blood transfusions. Nature 328: 719–21 (1987).

    Google Scholar 

  10. Gerberding, J. L. and D. K. Henderson. Design of rational infection control policies for human immunodeficiency virus infection. J. Infectious Diseases. Vol. 156, No. 6: 861–864 (1987).

    Article  Google Scholar 

  11. Anderson, R.M., R. M. May, G. F. Medley, and A. Johnson. A preliminary study of the transmission dynamics of the human immunodeficiency virus (HIV), the causative agent of AIDS. IMA J. Math. Med. Biol. 3: 229–263 (1986).

    Article  MathSciNet  MATH  Google Scholar 

  12. Anderson, R.M. and R. M. May. Transmission dynamics of HIV infection. Nature 326: 137–142 (1987).

    Article  Google Scholar 

  13. Castillo-Chavez, C., K. Cooke, W. Huang and S. A. Levin. On the role of long incubation periods in the dynamics of acquired immunodeficiency syndrome (AIDS) Part 1. Single population models. J. of Math. Biol.

    Google Scholar 

  14. Huang, W., C. Castillo-Chavez, K. Cooke and S. A. Levin. On the role of long incubation periods in the dynamics of acquired immunodeficiency syndrome (AIDS). Part 2. Multiple group models. In: Mathematical and statistical approaches to AIDS epidemiology (C. Castillo-Chavez, ed). Lecture Notes in Biomathematics, Springer-Verlag (in press).

    Google Scholar 

  15. Blythe, S. P. and R. M. Anderson. Distributed incubation and infectious periods in models of the transmission dynamics of the human immunodeficiency virus (HIV). IMA J. Math. Med. Bio. 5: 1–19 (1988).

    Article  MathSciNet  MATH  Google Scholar 

  16. Hethcote, H. W., H. W. Stech and P. van den Driessche. Periodicity and stability in epidemic models: a survey. In: Differential Equations and Applications in Ecology, Epidemics and Population Problems. S. Busenberg and K. L. Cooke (eds.) Academic Press, New York: 65–82 (1981).

    Google Scholar 

  17. Hyman, J. M. and E. A. Stanley. A risk based model for the spread of the AIDS virus. Math. Biosci. 90: 415–473 (1988).

    Article  MathSciNet  MATH  Google Scholar 

  18. Kingsley, R. A., R. Kaslow, C. R. Rinaldo Jr., K. Detre, N. Odaka, M. VanRaden, R. Detels, B. F. Polk, J. Chimel, S. F. Kersey, D. Ostrow and B. Visscher. Risk factors for seroconversion to human immunodeficiency virus among male homosexuals. The Lancet 1: 345–348 (1987).

    Article  Google Scholar 

  19. R. K. Miller. On the linearization of Volterra integral equations. J. Math. Anal. Appl. 23: 198–208 (1968).

    Article  MathSciNet  MATH  Google Scholar 

  20. S. O. Londen. Integral equations of Volterra type. In: Mathematics of Biology, M. lannelli (ed.), Liguori Editori, Napoli (1981).

    Google Scholar 

  21. J. K. Hale. Theory of Functional Differential Equations. Springer Verlag. New York (1977).

    Book  MATH  Google Scholar 

  22. R. Ross. The Prevention of Malaria. 2nd. Edition, Murray, London (1911).

    Google Scholar 

  23. Hethcote, H. W. and J. A. Yorke. Gonorrhea Transmission Dynamics and Control. Lecture Notes in Biomathematics No. 56, Springer VerlagHeidelberg (1984).

    Google Scholar 

  24. Castillo-Chavez, C., K. Cooke, W. Huang, and S. A. Levin. Results on the dynamics for models for the sexual transmission of the human immuno-deficiency virus. Applied Mathematics Letters.

    Google Scholar 

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© 1989 Springer-Verlag Berlin Heidelberg

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Castillo-Chavez, C., Cooke, K., Huang, W., Levin, S.A. (1989). The Role of Long Periods of Infectiousness in the Dynamics of Acquired Immunodeficiency Syndrome (AIDS). In: Castillo-Chavez, C., Levin, S.A., Shoemaker, C.A. (eds) Mathematical Approaches to Problems in Resource Management and Epidemiology. Lecture Notes in Biomathematics, vol 81. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-46693-9_14

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  • DOI: https://doi.org/10.1007/978-3-642-46693-9_14

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-51820-4

  • Online ISBN: 978-3-642-46693-9

  • eBook Packages: Springer Book Archive

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