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Constituents of Amniotic Fluid: Reflections of Normal and Abnormal Fetal Maturation

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Diagnosis and Treatment of Fetal Disorders

Abstract

In recent years there has been a rebirth of interest in the examination of the constituents of amniotic fluid as a possible means of assessing the condition of the intrauterine patient. Though individual samples of amniotic fluid have been subjected to examination through the centuries, little data had been gathered sequentially during gestation. The rather recent widespread use of amniocentesis, particularly in the Rh sensitized pregnancy, has made amniotic fluid available throughout gestation and has prompted comparative examination of fluid constituents at varying phases of fetal development.

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References

  • Andrews, B. F., W. M. Wolfe Jr., J. H. Hoffman, and P. K. Kalayil. Evaluation of amniotic fluid in the Rh sensitized mothers: first report of immunodiffusion studies. Southern Med. J. 59:1482, 1966.

    Google Scholar 

  • Behrman, R. E., J. T. Parer, and C. W. deLannoy. Placental growth and the formation of amniotic fluid. Nature 214:678, May 13, 1967.

    Article  PubMed  CAS  Google Scholar 

  • Betke, K. Bilirubin und Bilirubinausscheidung, in Die Physiologische Entwicklung Des Kindes. Friedrich Linneweh, ed. Berlin: Springer-Verlag, 1959.

    Google Scholar 

  • Bevis, D. C. A. The antenatal prediction of haemolytic disease of the newborn. Lancet 1:395, 1952.

    Article  PubMed  CAS  Google Scholar 

  • Bonsnes, R. W. Composition of amniotic fluid. Clin. Obstet. Gynec. 9:440, 1966.

    Article  PubMed  CAS  Google Scholar 

  • Brown, A. K. The significance of amniotic fluid pigment analysis in intrauterine transfusion and erythroblastosis fetalis. Report of the Fifty-third Ross Conference on Pediatric Research, Aspen, Colorado, March, 1966.

    Google Scholar 

  • Cassady, G., and J. Caillitau. The amniotic fluid in anencephaly. Ann. J. Obst. & Gynec. 97:395, 1967.

    CAS  Google Scholar 

  • Cherry, S. H., and R. E. Rosenfield. Intrauterine fetal transfusions for the management of erythroblastosis. Am. J. Obst. & Gynec. 98:275, 1967.

    CAS  Google Scholar 

  • Chez, R. A., F. G. Smith, and D. L. Hutchinson. Renal function in the intrauterine primate fetus. Am. J. Obst. & Gynec. 90:128, 1964.

    CAS  Google Scholar 

  • Elliot, P. M., and W. H. W. Inman. Volume of liquor amnii in normal and abnormal pregnancy. Lancet 2:835, 1961.

    Article  Google Scholar 

  • Finne, P. H. Erythropoietin levels in the amniotic fluid, particularly in the Rh immunized pregnancy. Acta Paediat. Scand. 53:269, 1964.

    Article  CAS  Google Scholar 

  • Finne, P. H. Antenatal diagnosis of the anemia in erythroblastosis. Acta Paediat. Scand. 55:609, 1966.

    Article  PubMed  CAS  Google Scholar 

  • Finne, P. H. Erythropoietin levels in cord blood as an indicator of intrauterine hypoxia. Acta Paediat. Scand. 55:478, 1966.

    Article  PubMed  CAS  Google Scholar 

  • Freda, V. The Rh problem in obstetrics and a new concept of its management using amniocentesis and spectrophotometric scanning of amniotic fluid. Am. J. Obst. & Gynec. 92:3, 1965.

    Google Scholar 

  • Fuchs, Fritz. Volume of amniotic fluid at various stages of pregnancy. Clin. Obstet. Gynec. 9:449, 1966.

    Article  PubMed  CAS  Google Scholar 

  • Gilbertsen, A. S., L. Bossenmaier, and R. Cardinal. Enterohepatic circulation of unconjugated bilirubin in man. Nature (London) 196:141, 1962.

    Article  CAS  Google Scholar 

  • Greene, John W., J. L. Duhring, and K. Smith. Placental function tests. Am. J. Obst. & Gynec. 92:1030, 1965.

    Google Scholar 

  • Hanon, F., M. Coquoin-Carnot, and P. Pignard. Le Liquide Amniotique. Masson et Cie, editors. Paris: Libraires de L’Academie de Medecine, 1955.

    Google Scholar 

  • Jeffcoate, T. N. A., and J. S. Scott. Polyhydramnios and oligohydramnios. Canad. Med. Assoc. J. 80:77, 1959.

    PubMed  CAS  Google Scholar 

  • Karunairatnam, M. C., L. Kerr, and G. Levvy. The glucuronide synthesizing system in the mouse and its relationship to β-glucuronidase. Biochem. J. 45:496, 1949.

    PubMed  CAS  Google Scholar 

  • Lester, R., and R. Schmid. Intestinal absorption of bile pigments. I. Enterhepatic circulation of bilirubin in the rat. J. Clin. Invest. 42:736, 1963.

    Article  PubMed  CAS  Google Scholar 

  • Liggins, G. C. Current indications for intrauterine transfusion, in Intrauterine Transfusion and Erythroblastosis Fetalis. Report of the Fifty-third Ross Conference on Pediatric Research, Aspen, Colorado, March, 1966.

    Google Scholar 

  • Liley, A. W. Liquor amnii analysis in the management of the pregnancy complicated by rhesus sensitization. Am. J. Obst. & Gynec. 82:1359, 1961.

    CAS  Google Scholar 

  • Liley, A. W. Errors in the assessment of hemolytic disease from amniotic fluid. Am. J. Obst. & Gynec. 86:485, 1963.

    CAS  Google Scholar 

  • Mandelbaum, B., G. La Croix, and M. Robinson. Determination of fetal maturity by spectrophotometric analysis of amniotic fluid. Obstet. Gynec. 29:471, 1967.

    PubMed  CAS  Google Scholar 

  • McKay, E. V. The management of isoimmunized pregnant women with particular reference to amniocentesis. Aust. J.Z.J. Obstet. Gynec. 1:78, 1961.

    Article  Google Scholar 

  • Pitkin, R. M., and S. J. Zwirek. Amniotic fluid creatinine. Am. J. Obst. & Gynec. 98:1135, 1967.

    CAS  Google Scholar 

  • Potter, E. L. Bilateral absence of ureters and kidneys. Obstet. Gynec. 25:3, 1965.

    PubMed  CAS  Google Scholar 

  • Schenker, S., N. H. Dawber, and R. Schmid. Bilirubin metabolism in the fetus. J. Clin. Invest. 43:32, 1964.

    Article  PubMed  CAS  Google Scholar 

  • Schreiner, W. E. Fructwasser und Fetus. New York: S. Karger, 1964.

    Google Scholar 

  • Seeds, A. E. Water metabolism of the fetus. Am. J. Obst. & Gynec. 92:727, 1965.

    Google Scholar 

  • Seeds, A. E. et al. Changes in amniotic fluid total solute concentration in Rhesus monkey. Am. J. Obst. & Gynec. 89:476, 1964.

    CAS  Google Scholar 

  • Vasicka, Alois. Oxygen in the amniotic fluid. Clin. Obstet. Gynec. 9:461, 1966.

    Article  PubMed  CAS  Google Scholar 

  • Walker, A. H. C. Liquor amnii studies in the prediction of hemolytic disease of the newborn. British Med. J. (ii):375, 1957.

    Google Scholar 

  • Ylppö, A. Zschrft. f. Kinderheilk 9:208, 1913, quoted by K. Betke. Bilirubin und Bilirubinausscheidung in Die Physiologische Entwicklung Des Kindes. Friedrich Linneweh, ed. Berlin: Springer-Verlag, 1959.

    Article  Google Scholar 

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Brown, A.K. (1968). Constituents of Amniotic Fluid: Reflections of Normal and Abnormal Fetal Maturation. In: Adamsons, K. (eds) Diagnosis and Treatment of Fetal Disorders. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-46172-9_8

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  • DOI: https://doi.org/10.1007/978-3-642-46172-9_8

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-46174-3

  • Online ISBN: 978-3-642-46172-9

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