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Current Topics in Microbiology and Immunology pp 152–176Cite as

Cellular Membrane Alterations in Neoplasia: A Review and a Unifying Hypothesis

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Part of the book series: Current Topics in Microbiology and Immunology ((CT MICROBIOLOGY,volume 47))

Abstract

Together with its abnormal growth, the neoplastic state is characterized by numerous and variable cellular derangements, but none of the many biochemical, immunological, biological and morphological defects hitherto described is common to all tumors. Moreover, even tumors induced by a single agent in a single cell type can have a multiplicity of phenotypes, which tend to modulate in time. Pleiomorphism thus constitutes a dominant aspect of neoplasia.

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  1. Biochemical Research Laboratory, Massachusetts General Hospital, Harvard Medical School, Boston, Mass., USA

    Donald F. Hoelzl Wallach

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  1. Genève, Switzerland

    W. Arber

  2. New Brunswick, USA

    W. Braun

  3. Göttingen, Germany

    F. Cramer

  4. Freiburg, Germany

    R. Haas

  5. Philadelphia, USA

    W. Henle  & H. Koprowski  & 

  6. München, Germany

    P. H. Hofschneider

  7. Frankfurt, Germany

    N. K. Jerne

  8. Prague, Czech Republic

    P. Koldovsky  & L. Syruček  & 

  9. Copenhagen, Denmark

    O. Maaløe

  10. Gießen, Germany

    R. Rott

  11. Wilbelmshaven, Germany

    H.-C. Schweiger

  12. Rehovoth, Israel

    M. Sela

  13. Seattle, USA

    P. K. Vogt

  14. Würzburg, Germany

    E. Wecker

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Wallach, D.F.H. (1969). Cellular Membrane Alterations in Neoplasia: A Review and a Unifying Hypothesis. In: Arber, W., et al. Current Topics in Microbiology and Immunology. Current Topics in Microbiology and Immunology, vol 47. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-46160-6_7

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