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Inhibitors Tools in Cell Research pp 301–317Cite as

The Inhibition of Adenine Nucleotide Translocation by Atractyloside

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Part of the book series: Colloquium der Gesellschaft für Biologische Chemie in Mosbach Baden ((MOSBACH,volume 20))

Abstract

Atractyloside occurs in the rhizomes of Atractylis gummifera (in German Mastix-Distel or Leim-Distel), a thistle growing in the southern mediterranean area. The ancient Egyptians already knew this drug as reported by Pedanios Dioskurides in “De Materia Medica”, Vol. III, which was written about 80 A.D. Dioskurides listed the drug as “Chamaileon Leukos”. Later it was known as an abortive agent. The isolation and crystallisation was reported in 1867 by Lefranc, who then named it atractylic acid.

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Authors and Affiliations

  1. Institut für Physiologische Chemie und Physikalische Biochemie, Universität München, Germany

    H. W. Heldt

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  1. H. W. Heldt
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  1. Institut für Physiologische Chemie und Physikalische Chemie, Universität München, D-8000, München 15, Goethestr. 33, Germany

    Th. Bücher  & H. Sies  & 

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Heldt, H.W. (1969). The Inhibition of Adenine Nucleotide Translocation by Atractyloside. In: Bücher, T., Sies, H. (eds) Inhibitors Tools in Cell Research. Colloquium der Gesellschaft für Biologische Chemie in Mosbach Baden, vol 20. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-46158-3_25

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  • DOI: https://doi.org/10.1007/978-3-642-46158-3_25

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-04441-3

  • Online ISBN: 978-3-642-46158-3

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