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Biological Significance of Structural Adenovirus Components

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Current Topics in Microbiology and Immunology

Part of the book series: Current Topics in Microbiology and Immunology ((CT MICROBIOLOGY,volume 43))

Abstract

Adenoviruses offer a number of advantages for integrated structural and biological studies of virus products. Most of the different serotypes can be produced in various cell systems with high yields. The major fraction of the products released from infected cells are structural components not aggregated in the form of intact virions or empty capsids. These components are soluble, in the true sense of the word, have dimensions making them accessible to electron microscopic analysis and in most cases exhibit a considerable stability. Furthermore they can be readily quantified by immunological or other sensitive biological techniques.

The author’s work presented in this review was supported by grants from the Swedish Medical Research Council (Projects no. K 67–16X–548–03 and B 67–16X–744–02B).

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  1. Department of Virology, Karolinska Institutet, School of Medicine, Stockholm, Sweden

    Erling Norrby

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  1. Genève, Switzerland

    W. Arber

  2. New Brunswick, USA

    W. Braun

  3. Göttingen, Germany

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  4. Freiburg, Germany

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  5. Philadelphia, USA

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  7. Frankfurt, Germany

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Norrby, E. (1968). Biological Significance of Structural Adenovirus Components. In: Arber, W., et al. Current Topics in Microbiology and Immunology. Current Topics in Microbiology and Immunology, vol 43. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-46118-7_1

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