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“Doctor, Why Are My Patch Tests Negative?”

  • Denis SassevilleEmail author
Chapter

Abstract

It is expected that patch testing will be negative in up to 50 % of patients. When competent investigators who use comprehensive series of allergens perform the procedure, a negative result will usually signify a diagnosis other than allergic contact dermatitis and will be deemed a true-negative test. False-negative tests are likely to occur when the allergens responsible for the dermatitis are not tested, when early or late readings are not performed, or when procedures such as photopatch tests and prick tests are omitted. Technical failure may arise from insufficient occlusion, short application times, and insufficient amount, concentration, or inactivity of the allergen. The patient may be in a state of unresponsiveness because of ultraviolet light exposure of medication-induced immunosuppression, again leading to falsely negative patch tests.

Keywords

Contact Dermatitis Patch Testing Allergic Contact Dermatitis Tinea Pedis Contact Allergy 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 2014

Authors and Affiliations

  1. 1.Division of Dermatology, Department of MedicineMcGill University Health Centre, Royal Victoria HospitalMontréalCanada

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