Semi-open (or Semi-occlusive) Tests

  • An E. GoossensEmail author


Semi-open (or semiocclusive) tests are useful modifications of patch testing for identifying potential allergenic products that have a certain irritation potential, such as antiseptic agents; cosmetic products containing emulsifiers, solvents, or other substances with an irritant potential, such as mascara, nail lacquers, hair dyes, shampoos, permanent-wave solutions, liquid soaps, and peelings; and household and industrial products such as paints, resins, varnish, glue, ink, wax, soluble oils, etc. Of course, the results need to be interpreted carefully and confirmed by testing with diluted products and certainly with the individual ingredients. Moreover, the pH of the products needs to be checked, and corrosive material should never be tested.


Patch Testing Sodium Lauryl Sulfate Contact Allergy Liquid Soap Antiseptic Agent 
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  1. 1.
    Goossens A. Minimizing the risks of missing a contact allergy. Dermatology. 2001;202:186–9.PubMedCrossRefGoogle Scholar
  2. 2.
    Lachapelle J-M, Maibach HI. Patch testing and prick testing. a practical guide. 3rd ed. Berlin/Heidelberg: Springer; 2012. p. 114–6.CrossRefGoogle Scholar
  3. 3.
    Goossens A. Alternatives aux patch-tests. Ann Dermatol Vénéréol. 2009;136:623–5.PubMedCrossRefGoogle Scholar
  4. 4.
    Frosch PJ, Geier J, Uter W, Goossens A. Patch testing with the patient’s own materials. Chapter 57. In: Contact dermatitis. 5th ed. Berlin/Heidelberg: Springer; 2011. p. 1107–19.CrossRefGoogle Scholar
  5. 5.
    Bruze M. Use of buffer solutions for patch testing. Contact Dermatitis. 1984;10:267–9.PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2014

Authors and Affiliations

  1. 1.Department of DermatologyKatholieke Universiteit LeuvenLeuvenBelgium

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