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Mood Disorders and Addiction

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Co-occurring Addictive and Psychiatric Disorders

Abstract

Comorbidity of mood and substance use disorders is the most common dual pathologies in the substance abuse field. High prevalence rates and challenging clinical management of patients diagnosed with this dual disorder imply a great burden for health care systems. Major Depression has been studied in comorbidity with the different drugs of abuse (e.g., alcohol, nicotine, cocaine, heroin, cannabis) with consistent findings throughout the world. Various neurobiological mechanisms are believed to play a role in the etiology of this comorbidity, often determining a severe clinical phenotype with poorer prognosis when compared to addiction and mood disorders only. Treatment of the co-occurrence of depression and substance use disorder involves an integrated approach, simultaneously addressing both the psychiatric and the addictive disorder. Current research into pharmacological—in particular antidepressant drugs—and psychosocial treatments has provided controversial results. More data are needed to develop stronger evidence for the treatment of comorbid major depression and substance use disorders.

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Authors and Affiliations

  1. Institute of Neuropsychiatry and Addiction, Hospital del Mar, IMIM-Hospital del Mar Medical Research Institute, Barcelona, Spain

    Marta Torrens & Paola Rossi

  2. Department of Psychiatry, Universitat Autònoma de Barcelona, Barcelona, Spain

    Marta Torrens

Authors
  1. Marta Torrens
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  2. Paola Rossi
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Correspondence to Marta Torrens .

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Editors and Affiliations

  1. Collaborative Psychiatric Research Institute, Antwerp University PC Alexian Brothers Boechout, Boechout, Belgium

    Geert Dom

  2. Clinical Psychological Service and Department, University Hospital of Psychiatry & University of Bern, Bern, Switzerland

    Franz Moggi

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Torrens, M., Rossi, P. (2015). Mood Disorders and Addiction. In: Dom, G., Moggi, F. (eds) Co-occurring Addictive and Psychiatric Disorders. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-45375-5_8

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  • DOI: https://doi.org/10.1007/978-3-642-45375-5_8

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  • Publisher Name: Springer, Berlin, Heidelberg

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