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Molecular Biology pp 93–107Cite as

Synthesis and Posttranslational Modifications of Proteins

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Part of the Lecture Notes in Computer Science book series (LNBI,volume 8248)

Abstract

Protein synthesis (translation) is a process in which more than one hundred macromolecules work together in a coordinated way. Translation is carried out on ribosomes by tRNA, and on the mRNA template sequence (ch. 3.3). Messenger RNA sequence is translated to the protein sequence. Translation starts from the 5’ end of the mRNA and follows to 3’ end strictly in accordance with ternary code (three nucleotides for one amino acid), that is according to the reading frame. Even a small change in the mRNA sequence can lead to the production of completely different protein, for example when amino acid codon is changed to a stop codon produced protein will be shorter. Frameshift can also occur.

Keywords

  • Endoplasmic Reticulum
  • Golgi Apparatus
  • Initiation Codon
  • Guanine Nucleotide Exchange Factor
  • Nuclear Export Signal

These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Authors and Affiliations

  1. Gliwice Branch, Maria Skłodowska-Curie Memorial Cancer Center and Institute of Oncology, Wybrzeże Armii Krajowej 15, 44-101, Gliwice, Poland

    Wiesława Widłak

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  1. Wiesława Widłak
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Editors and Affiliations

  1. Gliwice Branch, Maria Skłodowska-Curie Memorial Cancer Center and Institute of Oncology, Wybrzeże Armii Krajowej 15, 44-101, Gliwice, Poland

    Wiesława Widłak

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Widłak, W. (2013). Synthesis and Posttranslational Modifications of Proteins. In: Widłak, W. (eds) Molecular Biology. Lecture Notes in Computer Science(), vol 8248. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-45361-8_6

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  • DOI: https://doi.org/10.1007/978-3-642-45361-8_6

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-45360-1

  • Online ISBN: 978-3-642-45361-8

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