Abstract
Electrospinning is an efficient process for fabrication of polymeric ultrafine fibers with diameters ranging from sub-micrometer to nanometer. It involves the application of a strong electric field across a conductive capillary attaching to a polymer liquid-containing reservoir and a collector. The obtained ultrafine fibers exhibit several interesting characteristics, e.g., high surface area to mass or volume ratio, high porosity, vast possibilities for surface functionalization, etc. These unique characteristics make them used in various applications such as biomedical, pharmaceutical, and industrial applications, etc. Cellulose acetate, the acetate ester of cellulose, has been widely used as fibers. Recently, the electrospinning of cellulose acetate has been attracted due to its good thermal stability, chemical resistance, biocompatibility, biodegradability, etc. These properties render it suitable for use in various applications including tissue engineering, drug delivery system, wound dressing, separation membrane, etc. This chapter covers research related to electrospinning of cellulose acetate and the potential applications of cellulose acetate fibers.
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References
Formhals A (1934) Process and apparatus for preparing artificial threads. US Patent 1975504
Doshi J, Reneker DH (1995) Electrospinning process and applications of electrospun fibers. J Electrostat 35:151
Reneker DH, Chun I (1996) Nanometre diameter fibres of polymer, produced by electrospinning. Nanotechnology 7:216
Supaphol P, Suwantong O, Sangsanoh P, Neamnark A (2011) Electrospinning in drug delivery. In: Reisner DE (ed) Bionanotechnology II: global prospects. Boca Raton, CRC Press, p 455
Teo WE, Ramakrishna S (2006) A review on electrospinning design and nanofibre assemblies. Nanotechnology 17:R89
Greiner A, Wendorff JH (2007) Electrospinning: A fascinating method for the preparation of ultrathin fibers. Angew Chem 46:5670
Lannutti J, Reneker D, Ma T, Tomasko D, Farson D (2007) Electrospinning for tissue engineering scaffolds. Mater Sci Eng C 27:504
Sill TJ, von Recum HA (2008) Electrospinning: Applications in drug delivery and tissue engineering. Biomaterials 29:1989
Baumgarten P (1971) Electrostatic spinning of acrylic microfibers. J Colloid Interface Sci 36:71
Hayati I, Bailey AI, Tadros TF (1987) Investigations into the mechanisms of electrohydrodynamic spraying of liquids: Effect of electric-field and the environment on pendant drops and factors affecting the formation of stable jets and atomization. J Colloid Interface Sci 117:205
Deitzel JM, Kleinmeyer J, Harris D, Tan NCB (2001) The effect of processing variables on the morphology of electrospun nanofibers and textiles. Polymer 42:261
Meechaisue C, Dubin R, Supaphol P, Hoven VP, Kohn J (2006) Electrospun mat of tyrosine-derived polycarbonate fibers for potential use as tissue scaffolding material. J Biomat Sci Polym E 17:1039
Megelski S, Stephens JS, Chase DB, Rabolt JF (2002) Micro- and nanostructured surface morphology on electrospun polymer fibers. Macromolecules 22:8456
Deitzel JM, Kleinmeyer J, Hirvonen JK, Beck TNC (2001) Controlled deposition of electrospun poly(ethylene oxide) fibers. Polymer 42:8163
Jaeger R, Bergshoef MM, Batlle CMI, Schonherr H, Vancso GJ (1998) Electrospinning of ultra-thin polymer fibers. Macromol Symp 127:141
Jia H, Zhu G, Vugrinovich B, Kataphinan W, Reneker DH, Wang P (2002) Enzyme-carrying polymeric nanofibers prepared via electrospinning for use as unique biocatalysts. Biotechnol Prog 18:1027
Khil M-S, Cha D-I, Kim H-Y, Kim I-S, Bhattarai N (2003) Electrospun nanofibrous polyurethane membrane as wound dressing. J Biomed Mater Res A 67:675
Kim K, Luu YK, Chang C, Fang DF, Hsiao BS, Chu B, Hadjiargyrou M (2004) Incorporation and controlled release of a hydrophilic antibiotic using poly(lactide-co-glycolide)-based electrospun nanofibrous scaffolds. J Control Release 9:47
Ma Z, Kotaki M, Inai R, Ramakrishna S (2005) Potential of nanofiber matrix as tissue-engineering scaffolds. Tissue Eng 11:101
Ma Z, Kotaki M, Ramakrishna S (2006) Surface modified nonwoven polysulphone (PSU) fiber mesh by electrospinning: A novel afffinity membrane. J Membrane Sci 272:179
Luu YK, Kim K, Hsiao BS, Chu B, Hadjiargyrou M (2003) Development of nanostructured DNA delivery scaffold via electrospinning of PLGA and PLA-PEG block copolymers. J Control Release 89:341
Wang Y, Hsieh Y-L (2004) Enzyme immobilization to ultra-fine cellulose fibers via amphiphilic polyethylene glycol spacers. J Polym Sci Pol Chem 42:4289
Riboldi SA, Sampaolesi M, Neuenschwander P, Cossu G, Mantero S (2005) Electrospun degradable polyesterurethane membranes: Potential scaffolds for skeletal muscle tissue engineering. Biomaterials 26:4606
Wu L, Yuan X, Sheng J (2005) Immobilization of cellulase in nanofibrous PVA membranes by electrospinning. J Membrane Sci 250:167
Mark HF, Bikales NM, Overberger CG, Menges G (1985) Encyclopedia of polymer science and engineering. Wiley-Interscience, New York
Lu EX, Jiang ZQ, Zhang QZ, Jiang XG (2003) A water-insoluble drug monolithic osmotic tablet system utilizing gum arabic as an osmotic, suspending and expanding agent. J Control Release 92:375
Makhija SN, Vavia PR (2003) Controlled porosity osmotic pump-based controlled release systems of pseudoephedrine I. Cellulose acetate as a semipermeable membrane. J Control Release 89:5
Taepaiboon P, Rungsardthong U, Supaphol P (2007) Vitamin-loaded electrospun cellulose acetate nanofiber mats as transdermal and dermal therapeutic agents of vitamin A acid and vitamin E. Eur J Pharm Biopharm 67:387
Tungprapa S, Jangchud I, Supaphol P (2007) Release characteristics of four model drugs from drug-loaded electrospun cellulose acetate fiber mats. Polymer 48:5030
Suwantong O, Opanasopit P, Ruktanonchai U, Supaphol P (2007) Electrospun cellulose acetate fiber mats containing curcumin and release characteristic of the herbal substance. Polymer 48:7546
Son WK, Youk JH, Park WH (2006) Antimicrobial cellulose acetate nanofibers containing silver nanoparticles. Carbohydr Polym 65:430
Chen L, Bromberg L, Hatton TA, Rutledge GC (2008) Electrospun cellulose acetate fibers containing chlorhexidine as a bactericide. Polymer 49:1266
Suwantong O, Ruktanonchai U, Supaphol P (2008) Electrospun cellulose acetate fiber mats containing asiaticoside or Centella asiatica crude extract and the release characteristics of asiaticoside. Polymer 49:4239
Kontogiannopoulos KN, Assimopoulou AN, Tsivintzelis I, Panayiotou C, Papageorgiou VP (2011) Electrospun fiber mats containing shikonin and derivatives with potential biomedical applications. Int J Pharm 409:216
Gouma P, Xue R, Goldbeck CP, Perrotta P, Balázsi C (2012) Nano-hydroxyapatite-Cellulose acetate composites for growing of bone cells. Mater Sci Eng C 32:607
Liu H, Hsieh YL (2002) Ultra-fine fibrous cellulose membranes from electrospinning of cellulose acetate. J Polym Sci Pol Phys 40:2119
Son WK, Youk JH, Lee TS, Park YH (2004) Electrospinning of ultrafine cellulose acetate fibers: Studies of a new solvent system and deacetylation of ultrafine cellulose acetate fibers. Polym Sci Pol Phys 42:5
Ding B, Kimura E, Sato T, Fujita S, Shiratori S (2004) Fabrication of blend biodegradable nanofibrous nonwoven mats via multi-jet electrospinning. Polymer 45:1895
Tungprapa S, Puangparn T, Weerasombut M, Jangchud I, Fakum P, Semongkhol S, Meechaisue C, Supaphol P (2007) Electrospun cellulose acetate fibers: effect of solvent system on morphology and fiber diameter. Cellulose 14:563
Zhang L, Hsieh Y-L (2008) Ultra-fine cellulose acetate/poly(ethylene oxide) biocomponent fibers. Carbohydr Polym 71:196
Han SO, Youk JH, Min KD, Kang YO, Park WH (2008) Electrospinning of cellulose acetate nanofibers using a mixed solvent of acetic acid/water: Effects of solvent composition on the fiber diameter. Mater Lett 62:759
Wongsasulak S, Patapeejumruswong M, Weiss J, Supaphol P (2010) Electrospinning of food-grade nanofibers from cellulose acetate and egg albumen blends. J Food Eng 98:370
Greish YE, Meetani MA, Al Matroushi EA, Al Shamsi B (2010) Effects of thermal and chemical treatments on the structural stability of cellulose acetate nanofibers. Carbohydr Polym 82:569
Chen C, Wang L, Huang Y (2011) Electrospun phase change fibers based on polyethylene glycol/cellulose acetate blends. Appl Energy 88:3133
Baek W-I, Pant HR, Nam K-T, Nirmala R, Oh H-J, Kim I, Kim H-Y (2011) Effect of adhesive on the morphology and mechanical properties of electrospun fibrous mat of cellulose acetate. Carbohydr Res 346:1956
Castillo-Ortega MM, Nájera-Luna A, RodrÃguez-Félix DE, Encinas JC, RodrÃguez-Félix F, Romero J, Herrera-Franco PJ (2011) Preparation, characterization and release of amoxicillin from cellulose acetate and poly(vinyl pyrrolidone) coaxial electrospun fibrous membranes. Mater Sci Eng C 31:1772
Shuiping L, Lianjiang T, Weili H, Xiaoqiang L, Yanmo C (2010) Cellulose acetate nanofibers with photochromic property: Fabrication and characterization. Mater Lett 64:2427
Mao X, Ding B, Wang M, Yin Y (2010) Self-assembly of phthalocyanine and polyacrylic acid composite multilayers on cellulose nanofibers. Carbohydr Polym 80:839
Ma Z, Kotaki M, Ramakrishna S (2005) Electrospun cellulose nanofiber as affinity membrane. J Membrane Sci 265:115
Ritcharoen W, Supaphol P, Pavasant P (2008) Development of polyelectrolyte multilayer-coated electrospun cellulose acetate fiber mat as composite membranes. Eur Polym J 44:3963
Zhang L, Menkhaus TJ, Fong H (2008) Fabrication and bioseparation studies of adsorptive membranes/felts made from electrospun cellulose acetate nanofibers. J Membrane Sci 319:176
Sueyoshi Y, Fukushima C, Yoshikawa M (2010) Molecularly imprinted nanofiber membranes from cellulose acetate aimed for chiral separation. J Membrane Sci 357:90
Tian Y, Wu M, Liu R, Li Y, Wang D, Tan J, Wu R, Huang Y (2011) Electrospun membrane of cellulose acetate for heavy metal ion adsorption in water treatment. Cabohydr Polym 83:743
Huang X-J, Chen P-C, Huang F, Ou Y, Chen M-R, Xu Z-K (2011) Immobilization of Candida rugosa lipase on electrospun cellulose nanofiber membrane. J Mol Catal B Enzym 70:95
Anitha S, Brabu B, Thiruvadigal DJ, Gopalakrishnan C, Natarajan TS (2012) Optical, bactericidal and water repellent properties of electrospun nano-composite membranes of cellulose acetate and ZnO. Carbohydr Polym 87:1065
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Suwantong, O., Supaphol, P. (2015). Applications of Cellulose Acetate Nanofiber Mats. In: Pandey, J., Takagi, H., Nakagaito, A., Kim, HJ. (eds) Handbook of Polymer Nanocomposites. Processing, Performance and Application. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-45232-1_70
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DOI: https://doi.org/10.1007/978-3-642-45232-1_70
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