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9 Transcriptomics of Industrial Filamentous Fungi: A New View on Regulation, Physiology, and Application

Part of the The Mycota book series (MYCOTA,volume 13)

Abstract

The filamentous fungi Aspergillus niger, A. oryzae, Penicillium chrysogenum and Trichoderma reesei represent an important group of industrial production hosts with unique properties in relation to metabolite and protein production. They serve as a major resource for applications and processes in areas such as food, feed, antibiotics, biofuel and chemical production. With the newly emerged ‘-omics’ era, system-wide insights into the genomic repertoire and physiology of industrial fungi are possible, and the last few years have therefore witnessed great advances in the understanding of their metabolic potential. This review summarizes the transcriptomics insights recently gained into gene regulation and physiology of these industrial cell factories. New concepts and ideas derived from this perspective that aim to engineer fungal metabolism for more sustainable bioprocesses and novel products are highlighted and discussed.

Keywords

  • Filamentous Fungus
  • Unfold Protein Response
  • Itaconic Acid
  • Kojic Acid
  • Massively Parallel Signature Sequencing

These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Fig. 9.1.

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Nitsche, B.M., Meyer, V. (2014). 9 Transcriptomics of Industrial Filamentous Fungi: A New View on Regulation, Physiology, and Application. In: Nowrousian, M. (eds) Fungal Genomics. The Mycota, vol 13. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-45218-5_9

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