Abstract
Studies for investigating dentin hypersensitivity are either epidemiological or testing for the effectiveness of a possible treatment. The latter can be tested in vitro or in vivo. The myriad number of studies evaluating possible treatments for the condition mandates the adoption of rigid criteria for the conduction of such studies in order to validate their results. Literature will be reviewed in this chapter to evaluate the different testing methods for the effectiveness of dentin hypersensitivity treatments.
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References
Abed AM, Mahdian M, Seifi M, Ziaei SA, Shamsaei M (2011) Comparative assessment of the sealing ability of Nd:YAG laser versus a new desensitizing agent in human dentinal tubules: a pilot study. Odontology 99(1):45–48. doi:10.1007/s10266-010-0136-1
Ahmed TR, Mordan NJ, Gilthorpe MS, Gillam DG (2005) In vitro quantification of changes in human dentine tubule parameters using SEM and digital analysis. J Oral Rehabil 32(8):589–597. doi:10.1111/j.1365-2842.2005.01473.x, JOR1473 [pii]
Dijkman GE, Jongebloed WL, de Vries J, Ogaard B, Arends J (1994) Closing of dentinal tubules by glutaraldehyde treatment, a scanning electron microscopy study. Scand J Dent Res 102(3):144–150
Earl JS, Leary RK, Muller KH, Langford RM, Greenspan DC (2011) Physical and chemical characterization of dentin surface following treatment with NovaMin technology. J Clin Dent 22(3):62–67
Gillam DG, Khan N, Mordan NJ, Barber PM (1999) Scanning electron microscopy (SEM) investigation of selected desensitizing agents in the dentine disc model. Endod Dent Traumatol 15(5):198–204
Holland GR, Narhi MN, Addy M, Gangarosa L, Orchardson R (1997) Guidelines for the design and conduct of clinical trials on dentine hypersensitivity. J Clin Periodontol 24(11):808–813
Jain P, Vargas MA, Denehy GE, Boyer DB (1997) Dentin desensitizing agents: SEM and X-ray microanalysis assessment. Am J Dent 10(1):21–26
Lynch E, Brauer DS, Karpukhina N, Gillam DG, Hill RG (2012) Multi-component bioactive glasses of varying fluoride content for treating dentin hypersensitivity. Dent Mater 28(2):168–178. doi:10.1016/j.dental.2011.11.021, S0109-5641(11)00922-5 [pii]
Mordan NJ, Barber PM, Gillam DG (1997) The dentine disc. A review of its applicability as a model for the in vitro testing of dentine hypersensitivity. J Oral Rehabil 24(2):148–156
Pereira JC, Segala AD, Gillam DG (2005) Effect of desensitizing agents on the hydraulic conductance of human dentin subjected to different surface pre-treatments – an in vitro study. Dent Mater 21(2):129–138. doi:10.1016/j.dental.2004.02.007, S0109564104000417 [pii]
Sauro S, Gandolfi MG, Prati C, Mongiorgi R (2006) Oxalate-containing phytocomplexes as dentine desensitisers: an in vitro study. Arch Oral Biol 51(8):655–664. doi:10.1016/j.archoralbio.2006.02.010, S0003-9969(06)00038-0 [pii]
Suge T, Kawasaki A, Ishikawa K, Matsuo T, Ebisu S (2008) Ammonium hexafluorosilicate elicits calcium phosphate precipitation and shows continuous dentin tubule occlusion. Dent Mater 24(2):192–198. doi:10.1016/j.dental.2007.03.009, S0109-5641(07)00082-6 [pii]
Thanatvarakorn O, Nakashima S, Sadr A, Prasansuttiporn T, Ikeda M, Tagami J (2013) In vitro evaluation of dentinal hydraulic conductance and tubule sealing by a novel calcium-phosphate desensitizer. J Biomed Mater Res B Appl Biomater 101(2):303–309. doi:10.1002/jbm.b.32840
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Taha, S., Clarkson, B.H. (2014). Evaluating Study Designs to Investigate Dentin Hypersensitivity. In: Taha, S., Clarkson, B. (eds) Clinician's Guide to the Diagnosis and Management of Tooth Sensitivity. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-45164-5_7
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DOI: https://doi.org/10.1007/978-3-642-45164-5_7
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