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Rehabilitation After Cartilage Reconstruction

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Talar Osteochondral Defects

Abstract

Intact articular cartilage surfaces are necessary for smooth motion and pain-free function within the ankle joint. Healthy cartilage surfaces reduce the coefficient of friction, limit peaks of stress, and protect the joint from wear. Damage to the articular cartilage often leads to pain and dysfunction of the joint with limited potential for self-repair [24, 36]. If patients fail conservative management of symptomatic cartilage lesions, several treatment options exist for surgical restoration.

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References

  1. Alford JW, Cole BJ. Cartilage restoration, part 1: basic science, historical perspective, patient evaluation, and treatment options. Am J Sports Med. 2005;33:295–306.

    Article  PubMed  Google Scholar 

  2. Alford JW, Cole BJ. Cartilage restoration, part 2: techniques, outcomes, and future directions. Am J Sports Med. 2005;33:443–60.

    Article  PubMed  Google Scholar 

  3. Aurich M, Bedi HS, Smith PJ, Rolauffs B, Muckley T, Clayton J, Blackney M. Arthroscopic treatment of osteochondral lesions of the ankle with matrix-associated chondrocyte implantation: early clinical and magnetic resonance imaging results. Am J Sports Med. 2011;39(2):311–9.

    Article  PubMed  Google Scholar 

  4. Bazaz R, Ferkel RD. Treatment of osteochondral lesions of the talus with autologous chondrocyte implantation. Tech Foot Ankle Surg. 2004;3(1): 45–52.

    Article  Google Scholar 

  5. Biosurgery G. Carticel Package Insert. Edited June 2007. Genzyme Biosurgery, A division of Genzyme Corporation. http://www.carticel.com. Cambridge, MA.

  6. Breinan H, Minas T, Hsu HP, Nehrer S, Sledge CB, Spector M. Effect of cultured autologous chondrocytes on repair of chondral defects in a canine model. J Bone Joint Surg Am. 1997;79:1439–51.

    CAS  PubMed  Google Scholar 

  7. Brittberg M, Lindahl A, Nilsson A, Ohlsson C, Isaksson O, Peterson L. Treatment of deep cartilage defects in the knee with autologous chondrocyte transplantation. N Engl J Med. 1994;331:889–95.

    Article  CAS  PubMed  Google Scholar 

  8. Brittberg M, Peterson L, Sjogren-Jansson E, Tallheden T, Lindahl A. Articular cartilage engineering with autologous chondrocyte transplantation: a review of recent developments. J Bone Joint Surg Am. 2003;85 Suppl 3:109–15.

    PubMed  Google Scholar 

  9. Cherubino P, Grassi FA, Bulgheroni P, Ronga M. Autologous chondrocyte implantation using a bilayer collagen membrane: a preliminary report. J Orthop Surg (Hong Kong). 2003;11(1):10–5.

    CAS  Google Scholar 

  10. Chin TY, Mussett S, Ferkel R, Glazebrook M, Tak-Choy Lau J. Osteochondral lesions of the talar dome: autologous chondrocyte implantation. In: Johnson DH, Amendola A, Field LD, Richmond JC, Sgaglione NA, editors. Operative arthroscopy. 4th ed. Philadelphia: Lippincott Williams & Wilkins; 2013. p. 1024–34.

    Google Scholar 

  11. Dixon S, Harvey L, Baddour E, Janes G, Hardisty G. Functional outcome of matrix-associated autologous chondrocyte implantation in the ankle. Foot Ankle Int. 2011;32(4):368–74.

    Article  PubMed  Google Scholar 

  12. Giannini S, Buda R, Grigolo B, Vannini F. Autologous chondrocytes transplantation in osteochondral lesions of the ankle joint. Foot Ankle Int. 2001;22:513–7.

    CAS  PubMed  Google Scholar 

  13. Giannini S, Buda R, Grigolo B, Vannini F, De Franceschi L, Facchini A. The detached osteochondral fragment as a source of cells for autologous chondrocyte implantation (ACI) in the ankle joint. Osteoarthritis Cartilage. 2005;13(7):601–7.

    Article  CAS  PubMed  Google Scholar 

  14. Giannini S, Buda R, Vannini F, Di Caprio F, Grigolo B. Arthroscopic autologous chondrocyte implantation in osteochondral lesions of the talus: surgical technique and results. Am J Sports Med. 2008;36(5): 873–80.

    Article  PubMed  Google Scholar 

  15. Gibson AJ, McDonnell SM, Price AJ. Matrix-induced autologous chondrocyte implantation. Oper Tech Orthop. 2006;16(4):262–5.

    Article  Google Scholar 

  16. Gillogly SD, Myers TH. Treatment of full-thickness chondral defects with autologous chondrocyte implantation. Orthop Clin North Am. 2005;36(4): 433–46.

    Article  PubMed  Google Scholar 

  17. Gillogly SD, Voight M, Blackburn T. Treatment of articular cartilage defects of the knee with autologous chondrocyte implantation. J Orthop Sports Phys Ther. 1998;28:241–51.

    Article  CAS  PubMed  Google Scholar 

  18. Giza E, Nathe R, Kim J. Talus osteochondritis dissecans: treatment with matrix-based autologous chondrocyte implantation. Tech Orthop. 2010;25(4): 231–6.

    Article  Google Scholar 

  19. Giza E, Sullivan M, Ocel D, et al. Matrix-induced autologous chondrocyte implantation of talus articular defects. Foot Ankle Int. 2010;31(9):747–53.

    Article  PubMed  Google Scholar 

  20. Hambly K, Bobic V, Wondrasch B, Van Assche D, Marlovits S. Autologous chondrocyte implantation postoperative care and rehabilitation. Am J Sports Med. 2006;34:1020–38.

    Article  PubMed  Google Scholar 

  21. Horas U, Pelinkovic D, Herr G, Aigner T, Schnettler R. Autologous chondrocyte implantation and osteochondral cylinder transplantation in cartilage repair of the knee joint: a prospective, comparative trial. J Bone Joint Surg Am. 2003;85:185–92.

    PubMed  Google Scholar 

  22. Ikenoue T, Trindade MC, Lee MS, Lin EY, Schurman DJ, Goodman SB, Smith RL. Mechanoregulation of human articular chondrocyte aggrecan and type II collagen expression by intermittent hydrostatic pressure in vitro. J Orthop Res. 2003;21(1):110–6.

    Article  CAS  PubMed  Google Scholar 

  23. Koulalis D, Schultz W, Heyden M. Autologous chondrocyte transplantation for osteochondritis dissecans of the talus. Clin Orthop Relat Res. 2002;395: 186–92.

    Article  PubMed  Google Scholar 

  24. Krishnan SP, Skinner JA, Carrington RW, Flanagan AM, Briggs TW, Bentley G. Collagen-covered autologous chondrocyte implantation for osteochondritis dissecans of the knee: two- to seven-year results. J Bone Joint Surg Br. 2006;88:203–5.

    Article  CAS  PubMed  Google Scholar 

  25. Kwak S, Ferkel RD. Autologous chondrocyte implantation of the ankle: 2 to 10 year follow-up. AAOS annual meeting podium presentation, San Diego; 2011. Submitted for publication.

    Google Scholar 

  26. Lynn AK, Brooks RA, Bonfield W, Rushton N. Repair of defects in articular joints. Prospects for material-based solutions in tissue engineering. J Bone Joint Surg Br. 2004;86(8):1093–9.

    Article  CAS  PubMed  Google Scholar 

  27. Mandelbaum BR, Gerhardt MB, Peterson L. Autologous chondrocyte implantation of the talus. Arthroscopy. 2003;19 Suppl 1:129–37.

    Article  PubMed  Google Scholar 

  28. Marlovits S, Striessnig G, Kutscha-Lissberg F, Resinger C, Aldrian SM, Vecsei V, Trattnig S. Early postoperative adherence of matrix-induced autologous chondrocyte implantation for the treatment of full-thickness cartilage defects of the femoral condyle. Knee Surg Sports Traumatol Arthrosc. 2005;13(6):451–7.

    Article  PubMed  Google Scholar 

  29. Minas T, Peterson L. Chondrocyte transplantation. Oper Tech Orthop. 1997;4:323–33.

    Article  Google Scholar 

  30. Mitchell ME, Giza E, Sullivan MR. Cartilage transplantation techniques for talar cartilage lesions. J Am Acad Orthop Surg. 2009;17(7):407–14.

    PubMed  Google Scholar 

  31. Nam E, Ferkel R, Applegate G. Autologous chondrocyte implantation of the ankle. A 2- to 5-year follow-up. Am J Sports Med. 2009;37(2):274–84.

    Article  PubMed  Google Scholar 

  32. Peterson L, Brittberg M, Kiviranta I, Akerlund EL, Lindahl A. Autologous chondrocytes transplantation: biomechanics and long-term durability. Am J Sports Med. 2002;30:2–12.

    PubMed  Google Scholar 

  33. Peterson L, Brittberg M, Lindahl A. Autologous chondrocyte trans-plantation of the ankle. Foot Ankle Clin. 2003;8:291–303.

    Article  Google Scholar 

  34. Peterson L, Minas T, Brittberg M, Nilsson A, Sjogren-Jansson E, Lindahl A. Two- to 9-year outcome after autologous chondrocyte transplantation of the knee. Clin Orthop Relat Res. 2000;374:212–34.

    Article  PubMed  Google Scholar 

  35. Ronga M, Grassi FA, Montoli C, Bulgheroni P, Genovese E, Cherubino P. Treatment of deep cartilage defects of the ankle with matrix-induced autologous chondrocyte implantation (MACI). Foot Ankle Surg. 2005;11(1):29–33.

    Article  Google Scholar 

  36. Salter RB, Simmonds DF, Malcolm BW, Rumble EJ, MacMichael D, Clements ND. The biological effect of continuous passive motion on the healing of full-thickness defects in articular cartilage: an experimental investigation in the rabbit. J Bone Joint Surg Am. 1980;62:1232–51.

    CAS  PubMed  Google Scholar 

  37. Schneider TE, Karaikudi S. Matrix-Induced Autologous Chondrocyte Implantation (MACI) grafting for osteochondral lesions of the talus. Foot Ankle Int. 2009;30(9):810–4.

    Article  PubMed  Google Scholar 

  38. Schuman L, Struijs PA, van Dijk CN. Arthroscopic treatment for osteochondral defects of the talus. Results at follow-up at 2 to 11 years. J Bone Joint Surg Br. 2002;84(3):364–8.

    Article  CAS  PubMed  Google Scholar 

  39. Zheng MH, King E, Kirilak Y, Huang L, Papadimitriou JM, Wood DJ, Xu J. Molecular characterisation of chondrocytes in autologous chondrocyte implantation. Int J Mol Med. 2004;13(5):623–8.

    CAS  PubMed  Google Scholar 

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Conflict of Interest

The author has no current conflict of interests with the products presented

Author information

Authors and Affiliations

  1. Department of Orthopaedic Surgery, Southern California Orthopedic Institute, University of California, Los Angeles, Van Nuys, CA, USA

    Tomasz T. Antkowiak MD, MS

  2. Department of Orthopaedic Surgery, University of California, Los Angeles, Los Angeles, CA, USA

    Richard D. Ferkel MD

  3. Southern California Orthopedic Institute, Van Nuys, CA, USA

    Richard D. Ferkel MD

  4. Department of Orthopaedic Surgery, St Vincent’s Clinic, Sydney, NSW, Australia

    Martin R. Sullivan MBBS(Hons), FRACS, FAOrthA

  5. Department of Orthopaedic Surgery, Sutter Auburn Orthopaedics, Sutter Medical Group, Auburn, CA, USA

    Christopher D. Kreulen MD,MS

  6. Department of Orthopaedics, Foot and Ankle Surgery, University of California, Davis, 4860 Y Street, Suite 3800, Sacramento, CA, 95817, USA

    Eric Giza MD

  7. Department of Orthopaedics, University of California, Davis, 4860 Y Street, Suite 3800, Sacramento, CA, 95817, USA

    Scott R. Whitlow MD

Authors
  1. Tomasz T. Antkowiak MD, MS
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  2. Richard D. Ferkel MD
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  3. Martin R. Sullivan MBBS(Hons), FRACS, FAOrthA
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  4. Christopher D. Kreulen MD,MS
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  5. Eric Giza MD
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  6. Scott R. Whitlow MD
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Corresponding author

Correspondence to Richard D. Ferkel MD .

Editor information

Editors and Affiliations

  1. Orthopaedic Surgery, University of Amsterdam Academic Medical Centre, Amsterdam, The Netherlands

    C. Niek van Dijk

  2. Orthopaedic Surgery and Traumatology, Hospital for Special Surgery, New York, New York, USA

    John G. Kennedy

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© 2014 ESSKA

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Antkowiak, T.T., Ferkel, R.D., Sullivan, M.R., Kreulen, C.D., Giza, E., Whitlow, S.R. (2014). Rehabilitation After Cartilage Reconstruction. In: van Dijk, C., Kennedy, J. (eds) Talar Osteochondral Defects. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-45097-6_16

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  • DOI: https://doi.org/10.1007/978-3-642-45097-6_16

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-45096-9

  • Online ISBN: 978-3-642-45097-6

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