Zusammenfassung
Das Kapitel beschreibt die praktische Messung der otoakustischen Emissionen (OAE) sowie ihre Bewertung und audiologische Interpretation, in Bezug sowohl auf die von linearen Anteilen bereinigten transitorisch (mit Klick-Reizen) evozierten OAE (TEOAE) als auch auf die auf nichtlinearen Verzerrungen des Innenohres beruhenden otoakustischen Distorsionsprodukte (DPOAE). Breiten Raum nimmt die Beurteilung der Messbedingungen in Bezug auf Sondenlage und Störsignaleinfluss ein. Mit Hilfe der Begriffe Stabilität, Restrauschen, Reproduzierbarkeit und Signal/Rausch-Verhältnis gelingt die Unterscheidung zwischen objektiv abwesenden Reizantworten und solchen, die sich dem Nachweis entziehen. Der in Screening-Geräten angewendete automatische Signalnachweis beruht auf signalstatistischen Verfahren, die auf eine hohe Sensitivität getrimmt sind. Frequenzspezifität und Wachstumsfunktionen werden diskutiert, ebenso wie die auf der efferenten Steuerung der Haarzellen beruhende und bei der Erkennung bestimmter Funktionsstörungen sehr aufschlussreiche kontralaterale Suppression der OAE durch kontralaterale akustische Stimulation.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Literatur
Abdala C (2000) Distortion product otoacoustic emission (2f1-f2) amplitude growth in human adults and neonates. J Acoust Soc Am 107(1):446–456
Abdala C, Dhar S (2012) Maturation and aging of the human cochlea: A view through the DPOAE looking glass. JARO 13:403–421
Abdala C, Sininger YS, Starr A (2000) Distortion product otoacoustic emissions suppression in subjects with auditory neuropathy. Ear Hear 21:542–553
Attias J, Furst M, Furman V, Reshef I, Horowitz G, Bresloff I (1995) Noise-induced otoacoustic emission loss with or without hearing loss. Ear Hear 16(6):612–618
Berlin CI, Hood LJ, Hurley A, Wen H (1993) Contralateral suppression of non-linear click-evoked otoacoustic emissions. Hear Res 71:1–11
Boege P, Janssen T (2002) Pure-tone threshold estimation from extrapolated distortion product otoacoustic emission I/O-functions in normal and cochlear hearing loss ears. J Acoust Soc Am 111(4):1810–1818
Bönnhoff S, Hoth S (1993) Die Stabilität der transitorisch evozierten otoakustischen Emissionen und ihre Eignung zum Nachweis von Veränderungen des Hörvermögens. Audiol Akust 32:32–53
Collet L, Kemp DT, Veuillet E, Duclaux R, Moulin A, Morgon A (1990) Effect of contralateral auditory stimulation on active cochlear micro-mechanical properties in human subjects. Hear Res 43:251–261
Collet L, Veuillet E, Bene J, Morgon A (1992) Effects of contralateral white noise on click-evoked emissions in normal and sensorineural ears: Towards an exploration of the medial olivocochlear system. Audiology 31:1–7
De Boer J, Thornton RD, Krumbholz K (2012) What is the role of the medial olivcochlear system in speech-in-noise processing? J Neurophysiol 107:1301–1312
Dalhoff E, Turcanu D, Vetešník A, Gummer AW (2013) Two-source interference as the major reason for auditory-threshold estimation error based on DPOAE input-output functions in normal-hearing subjects. Hear Res 296:67–82
Dhar S, Talmadge CL, Long GR, Tubis A (2002) Multiple internal reflections in the cochlea and their effect on DPOAE fine structure. J Acoust Soc Am 112(6):2882–2897
Durante AS, Carvallo RM (2008) Contralateral suppression of linear and nonlinear transient evoked otoacoustic emissions in neonates at risk for hearing loss. J Commun Disord 41(1):70–83
Engdahl B, Tambs K, Hoffmann HJ (2013) Otoacoustic emissions, pure-tone audiometry, and self-reported hearing. Int J Audiol 52(2):74–82
Ernst A, Lenarz T (1997) Otoacoustic emissions in predicting noise induced hearing loss in vulnerable inner ears. In:European commission concerted action – protection against noise. University college London, ILO April 16–19, abstract page 35
Gehr DD, Janssen T, Michaelis CE, Deingruber K, Lamm K (2004) Middle ear and cochlear disorders result in different DPOAE growth behavior: Implications for the differentiation of sound conductive and cochlear hearing loss. Hear Res 193:9–19
Gorga MP, Neely ST, Bergman BM, Beauchaine KL, Kaminski JR, Peters J, Schulte L, Jesteadt W (1993) A comparison of transient-evoked and distortion product otoacoustic emissions in normal-hearing and hearing impaired subjects. J Acoust Soc Am 94(5):2639–2648
Gorga MP, Neely ST, Dorn PA, Brenda MH (2003) Further efforts to predict pure-tone thresholds from the distortion product otoacoustic emission input/output functions. J Acoust Soc Am 113:3275–3284
Guinan JJ (2006) Olicocochlear efferents:Anatomy, physiology, function, and the measurement of efferent effecs in humans. Ear Hear 27:589–607
Heitmann J, Waldmann B, Schnitzler HU, Plinkert PK, Zenner HP (1998) Suppression of distortion product otoacoustic emissions (DPOAE) near 2f1-f2 removes DP-gram fine structure – Evidence for a secondary generator. J Acoust Soc Am 103:1527–1531
Hood LJ, Berlin CI, Bordelon J, Rose K (2003) Patients with auditory neuropathy/dys-synchrony lack efferent suppression of transient evoked otoacoustic emissions. J Am Acad Audiol 14(6):302–313
Hoth S (1991) Zeitlich differentielle Analyse des Korrelationskoeffizienten: Eine Bereicherung bei der Auswertung von akustisch evozierten Potentialen. Audiol Akust 30:214–220
Hoth S (1995) Zusammenhang zwischen EOAE-Parametern und Hörverlust (Relationship between parameters of evoked otoacoustic emissions and hearing loss). Audiol Akust 34:20–29
Hoth S (1996) Der Einfluß von Innenohrhörstörungen auf verzögerte otoakustische Emissionen (TEOAE) und Distorsionsprodukte (DPOAE). Laryngol Rhinol Otol 75:709–718
Hoth S (2002) Korrelation zwischen Tonaudiogramm und Frequenzabhängigkeit der otoakustischen Emissionen. DGA 5. Jahrestagung Zürich. Tagungs-CD
Hoth S (2003) Warum sind TEOAE und DPOAE gegenüber cochleären Funktionsdefiziten unterschiedlich empfindlich? Z Audiol 42(2):48–50
Hoth S (2005) On a possible prognostic value of otoacoustic emissions. A study on patients with sudden hearing loss. Eur Arch Otorhinolaryngol 262(3):217–224
Hoth S, Bönnhoff S (1993) Klinische Anwendung der transitorisch evozierten otoakustischen Emissionen zur therapiebegleitenden Verlaufskontrolle. HNO 41:135–145
Hoth S, Böttcher P (2008) Nomenklatur und Diagramme bei der Beschreibung und Interpretation von OAE-Messungen. Z Audiol 47(4):140–149
Hoth S, Lenarz T (1997) Otoakustische Emissionen – Grundlagen und Anwendung. 2. Aufl. Thieme, Stuttgart, ISBN 3-13-127602-9
Hoth S, Neumann K (2006) Das OAE-Handbuch. Otoakustische Emissionen in der Praxis. Thieme, Stuttgart, ISBN-10: 3-13-142561-X/ISBN-13: 978-3-13-3142561-4
Hoth S, Neumann K (2006) Die diagnostische Aussagekraft der otoakustischen Emissionen. Praktische Arbeitsmedizin 6:18–24
Hoth S, Polzer M (2006) Qualität in Zahlen. Signalnachweis in der objektiven Audiometrie. Z Audiol 45(3):100–110
Hoth S, Weber F (2001) The latency of evoked otoacoustic emissions:Its relation to hearing loss and auditory evoked potentials. Scand Audiol 30:173–183
Hoth S, Gudmundsdottir K, Plinkert P (2010) Age dependence of otoacoustic emissions: The loss of amplitude is primarily caused by age-related hearing loss and not by aging alone. Eur Arch Otorhinolaryngol 267(5):679–690
Janssen T (2009) Otoakustische Emissionen. In Lehnhardt E, Laszig R (Hrsg) Praxis der Audiometrie, 9. Aufl. Thieme, Stuttgart, ISBN 3-13-369009-6
Janssen T, Gehr DD, Klein A, Müller J (2005) Distortion product otoacoustic emissions for hearing threshold estimation and differentiation between middle-ear and cochlear disorders in neonates. J Acoust Soc Am 117(5):2969–2979
Kalluri R, Shera CA (2001) Distortion-product source unmising:A test of the two-mechanism model for DPOAE generation. J Acoust Soc Am 109(2):622–637
Kandzia F, Oswald J, Janssen T (2011) Binaural measurement of bone conduction click evoked otoacoustic emissions in adults and infants. J Acoust Soc Am 129:1464–1474
Kapadia S, Lutman ME (1999) Reduced ‘audiogram ripple’ in normally-hearing subjects with weak otoacoustic emissions. Audiol 38:257–261
Keppler H, Dhooge H, Maes L, D’haenens W, Bockstael A, Philips B, Swinnen F, Vinck B (2010) Transient-evoked and distortion product otoacoustic emissions: A short-term test-retest reliability study. Int J Audiol 49:99–109
Konrad-Martin D, Neely ST, Keefe DH, Dorn PA, Gorga MP (2001) Sources of distortion product otoacoustic emissions revealed by suppression experiments and inverse fast Fourier transforms in normal ears. J Acoust Soc Am 109:2862–2879
Kumar UA, Methi R, Avinash MC (2013) Test/retest repeatability of effect contralateral acoustic stimulation on the magnitudes of distortion product otoacoustic emissions. Laryngoscope 123(2):463–471
Kummer P, Janssen T, Arnold W (1998) The level and growth behavior of the 2f1-f2 distortion product otoacoustic emission and its relationship to auditory sensitivity in normal hearing and cochlear hearing loss. J Acoust Soc Am 103:3431–3444
Kummer P, Janssen T, Hulin P, Arnold W (2000) Optimal L1-L2 primary tone level separation remains independent of test frequency in humans. Hearing Research 146:47–56
Lapsley Miller JA, Marshall L, Heller LM (2004) A longitudinal study of changes in evoked otoacoustic emissions and pure-tone thresholds as measured in a hearing conservation program. Int J Audiol 43:307–322
Liberman MC, Puria S, Guinan JJ Jr (1996) The ipsilaterally evoked olivocochlear reflex causes rapid adaptation of the 2f1-f2 distortion product otoacoustic emission. J Acoust Soc Am 99:3572–3584
Long GR, Talmadge CL, Lee J (2008) Measuring distortion product otoacoustic emissions using continuously sweeping primaries. J Acoust Soc Am 124(3):1613–1626
Lonsbury-Martin BL, Martin GK (2007) Otoacoustic Emissions. In: Burkard RF, Don M, Eggermont JJ (eds) Auditory evoked potentials. Basic principles and clinical application. Lippincott Williams & Wilkins, Baltimore, pp 159–180
Lucertini M, Moleti A, Sisto R (2002) On the detection of early cochlear damage by otoacoustic emission analysis. J Acoust Soc Am 111(2):972–978
Margolis RH, Trine MB (1997) Influence of middle-ear disease on otoacoustic emissions. In: Robinette MS, Glattke TJ (eds) Otoacoustic emissions: Clinical applications. Thieme, New York, pp 130–150
Marshall L, Heller LM (1996) Reliability of transient-evoked otoacoustic emissions. Ear Hear 17(3):237–256
McAlpine D, Johnstone BM (1990) The ototoxic mechanism of cisplatin. Hear Res 47:191–203
Moleti A, Sisto R, Lucertini M (2002) Linear and nonlinear transient evoked otoacoustic emissions in humans exposed to noise. Hear Res 174(1–2):290–295
Moser T, Strenzke N, Meyer A, Lesinski-Schiedat A, Lenarz T, Beutner D, Foerst A, Lang-Roth R, von Wedel H, Walger M, Gross M, Keilmann A, Limberger A, Steffens T, Strutz J (2006) Diagnosis and therapy of auditory synaptopathy/neuropathy. HNO 54(11):833–841
Moulin A, Collet L, Duclaux R (1993) Contralateral auditory stimulation alters acoustic distortion products in humans. Hear Res 65:193–210
Müller P, Kompis M (2002) Evaluation of a noise reduction system for the assessment of click-evoked otoacoustic emissions. J Acoust Soc Am 112(1):164–171
Plinkert PK, Lenarz T (1992) Evozierte otoakustische Emissionen und ihre Beeinflussung durch kontralaterale akustische Stimulation. Laryngol Rhinol Otol 71:74–78
Plinkert PK, Kröber S (1991) Früherkennung einer Cisplatin-Ototoxizität durch evozierte otoakustische Emissionen. Laryngol Rhinol Otol 70:457–462
Plinkert PK, Hemmert W, Zenner HP (1995) Methodenvergleich zur Früherkennung einer Lärmvulnerabilität des Innenohres. HNO 43:89–97
Plinkert PK, Hemmert W, Wagner W, Just K, Zenner HP (1999) Monitoring noise susceptibility: Sensitivity of otoacoustic emissions and subjective audiometry. Br J Audiol 33:367–382
Prieve BA, Gorga MP, Schmidt A, Neely S, Peters J, Schultes L, Jestaedt W (1993) Analysis of transient-evoked emissions in normal-hearing and hearing-impaired ears. J Acoust Soc Am 93:3308–3319
Probst R, Hauser R (1990) Distortion product otoacoustic emissions in normal and hearing-impaired ears. Am J Otolaryngol 11:236–243
Probst R, Lonsbury-Martin BL, Martin GK, Coats AC (1987) Otoacoustic emissions in ears with hearing loss. Am J Otolaryngol 8:73–81
Probst R, Harris FP (1997a) Otoacoustic emissions. In Alford BR, Jerger J, Jenkins HA (eds) Electrophysiologic evaluation in otolaryngology. Adv Otolaryngol 53. Karger, Basel, pp 182–204
Probst R, Harris FP (1997b) Otoacoustic emissions and audiometric outcomes. In: Robinette MS, Glattke TJ (eds.) Otoacoustic emissions: Clinical applications. Thieme, New York, pp 151–180
Puel JL, Rebillard G (1990) Effect of contralateral sound stimulation on the distortion product 2F1-F2: Evidence that the medial efferent system is involved. J Acoust Soc Am 87:1630–1635
Rödel R, Breuer T (1994) Evozierte otoakustische Emissionen und Mittelohrfunktion. Laryngol Rhinol Otol 73:118–122
Ryan S, Kemp DT, Hinchcliffe R (1991) The influence of contralateral acoustic stimulation on click-evoked otoacoustic emissions in humans. British J Audiol 25:391–397
Shera CA, Guinan JJ jr (1999) Evoked otoacoustic emissions arise by two fundamentally different mechanisms: a taxonomy for mammalian OAEs. J Acoust Soc Am 105(2):782–798
Stavroulaki P, Apostolopoulos N, Segas J, Tsakanikos M, Adamopoulos G (2001) Evoked otoacoustic emissions – an approach for monitoring cisplatin induced ototoxicity in children. Int J Ped Otorhinolaryngol 59:47–57
Talmadge CL, Tubis A, Long GR, Piskorski P (1998) Modeling otoacoustic emission and hearing threshold fine structures. J Acoust Soc Am 104(3):1517–1543
Talmadge CL, Long GR, Tubis A, Dhar S (1999) Experimental confirmation of the two-source interference model for the fine structure of distortion product otoacoustic emissions. J Acoust Soc Am 105:275–292
Talmadge CL, Tubis A, Long GR, Tong C (2000) Modeling the combined effects of basilar membrane nonlinearity and roughness on stimulus frequency otoacoustic emission fine structure. J Acoust Soc Am 108(6):2911–2932
Wagner W, Plinkert PK (1999) The relationship between auditory threshold and evoked otoacoustic emissions. Eur Arch Otorhinolaryngol 256:177–188
Wagner W, Heppelmann G, Müller J, Janssen T, Zenner HP (2007) Olivocochlear reflex effect on human distortion product otoacoustic emissions is largest at frequencies with distinct fine structure dips. Hear Res 223:83–92
Wagner W, Heppelmann G, Vonthein R, Zenner HP (2008) Test-Retest repeatability of distortion product otoacoustic emissions. Ear Hear 29(3):378–391
Waldmann B, Heitmann J, Plinkert PK (1997) »Single generator«-Distorsionsprodukte (sgDPOAE): Entwicklung eines neuen Präzisionsmeßsystems. Audiol Akust 36:22–31
Walger M, Foerst A, Beutner D, Streicher B, Stürmer K, Lang-Roth R (2011) Auditorische Synaptopathie/Neuropathie. Klinik und Diagnostik. HNO 59:414–424
Whitehead ML, Lonsbury-Martin BL, Martin GK (1992) Evidence for two discrete sources of 2f1-f2 distortion-product otoacoustic emission in rabbit: I. Differential dependence on stimulus parameters. J Acoust Soc Am 91:1587–1607
Whitehead ML, Lonsbury-Martin BL, Martin GK (1992) Evidence for two discrete sources of 2f1-f2 distortion-product otoacoustic emission in rabbit: II. Differential physiological vulnerability. J Acoust Soc Am 92:2662–2682
Yalçinkaya F, Yilmaz ST, Muluk NB (2010) Transient evoked otoacoustic emissions and contralateral suppression in children with auditory listening problems. Auris Nasus Larynx 37(1):47–54
Yang LP, Young ST, Kuo TS (2002) Effects of noise on transient-evoked oto-acoustic emission pass/fail criteria. Med Biol Eng Comp 40:278–281
Yilmaz S, Öktem F, Karaman E (2010) Detection of cisplatin-induced ototoxicity with transient evoked otoacoustic emission test before pure tone audiometer. Eur Arch Otorhinolaryngol 267:1041–1044
Zebian M, Kandzia F, Janssen T, Hensel J, Fedtke T (2013) Otoacoustic emissions stimulated by bone conduction – a review (Otoakustische Emissionen stimuliert über Knochenleitung – eine Übersicht). Z Audiol 52(3):96–106
Zhao F, Stephens D (1999) Test-retest variability of distortion-product otoacoustic emissions in human ears with normal hearing. Scand Audiol 28:171–178
Author information
Authors and Affiliations
Rights and permissions
Copyright information
© 2014 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
Walger, M., Hoth, S. (2014). Otoakustische Emissionen (OAE). In: Objektive Audiometrie im Kindesalter. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-44936-9_4
Download citation
DOI: https://doi.org/10.1007/978-3-642-44936-9_4
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-44935-2
Online ISBN: 978-3-642-44936-9
eBook Packages: Medicine (German Language)