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Zusammenfassung

Für die Pädiatrie klinisch wichtige Störungen des Lipidstoffwechsels umfassen Veränderungen der Plasmalipoproteine mit und ohne Hyperlipidämien, Lipidspeicherkrankheiten sowie Störungen der Fettsäureoxidation.

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Notes

  1. 1.

    Umrechnung in Stoffmengenkonzentration: mg/dl × 0,05551 = mmol/l.

Literatur

  • Amundsen AL, Ose L, Nenseter MS, Ntanios FY (2002) Plant sterol ester-enriched spread lowers plasma total and LDL cholesterol in children with familial hypercholesterolemia. Am J Clin Nutr 76: 338–344

    CAS  PubMed  Google Scholar 

  • Clauss S, Wai KM, Kavey RE, Kuehl K (2009) Ezetimibe treatment of pediatric patients with hypercholesterolemia. J Pediatr 154: 869–872

    Article  CAS  PubMed  Google Scholar 

  • Davidson MH (2011) A systematic review of bile acid sequestrant therapy in children with familial hypercholesterolemia. J Clin Lipidol 5:76–81

    Article  PubMed  Google Scholar 

  • Descamps OS, Tenoutasse S, Stephenne X et al. (2011) Management of familial hypercholesterolemia in children and young adults: consensus paper developed by a panel of lipidologists, cardiologists, paediatricians, nutritionists, gastroenterologists, general practitioners and a patient organization. Atherosclerosis 218: 272–280

    Article  CAS  PubMed  Google Scholar 

  • Eng CM, Guffon N, Wilcox WR et al. (2001) Safety and efficacy of recombinant human alpha-galactosidase A–replacement therapy in Fabry’s disease. N Engl J Med 345: 9–16

    Article  CAS  PubMed  Google Scholar 

  • ESPGAN Committee on Nutrition (1994) Comment on childhood diet and prevention of coronary heart disease. J Pediatr Gastroenterol Nutr 19: 261–269

    Google Scholar 

  • Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (2001) Executive Summary of the Third Report of the National Cholesterol Education Program (NCEP). Adult Treatment Panel III. JAMA 285: 2486–2497

    Article  Google Scholar 

  • Farnier M, Bruckert E (2012) Severe familial hypercholesterolaemia: Current and future management. Arch Cardiovasc Dis 105: 656–665

    Article  PubMed  Google Scholar 

  • Gotto AM Jr, Moon JE (2012) Management of cardiovascular risk: the importance of meeting lipid targets. Am J Cardiol 110 (1 Suppl): 3 A–14 A

    Article  CAS  PubMed  Google Scholar 

  • Hallikainen MA, Sarkkinen ES, Uusitupa MI (2000) Plant stanol esters affect serum cholesterol concentrations of hypercholesterolemic men and women in a dose-dependent manner. J Nutr 130: 767–776

    CAS  PubMed  Google Scholar 

  • Jaeger BR, Tsobanelis T, Bengel F, Schwaiger M, Seidel D (2002) Long-term prevention of premature coronary atherosclerosis in homozygous familial hypercholesterolemia. J Pediatr 141: 125–128

    Article  PubMed  Google Scholar 

  • Koletzko B, Ullrich K, Becker M, Beisiegel U, Schwandt P (1995) Diagnostik und Therapie der Hypercholesterinämie bei Kindern und Jugendlichen. Empfehlungen der Arbeitsgemeinschaft für Pädiatrische Stoffwechselstörungen. Monatsschr Kinderheilkd 143: 1041–1042

    Google Scholar 

  • Koletzko B, Dokoupil K, Schenk U von (1996) Hast Du auch hohes Cholesterin? Ein Ernährungsberater für Kinder und Eltern. Steinkopff, Darmstadt

    Book  Google Scholar 

  • LIPID Study Group (Long term Intervention with Pravastatin in-Ischaemic Disease) (2002) Long-term effectiveness and safety of pravastatin in 9014 patients with coronary heart disease and average cholesterol concentrations: the LIPID trial follow-up. Lancet 359: 1379–1387

    Article  Google Scholar 

  • Miettinen TA, Gylling H (1999) Regulation of cholesterol metabolism by dietary plant sterols. Curr Opin Lipidol 10: 9–14

    Article  CAS  PubMed  Google Scholar 

  • Penson MG, Fricker FJ, Thompson JR et al. (2001) Safety and efficacy of pravastatin therapy for the prevention of hyperlipidemia in pediatric and adolescent cardiac transplant recipients. J Heart Lung Transplant 20: 611–618

    Article  CAS  PubMed  Google Scholar 

  • Salen G, Bergmann K von, Lutjohann D et al.; Multicenter Sitosterolemia Study Group (2004) Ezetimibe effectively reduces plasma plant sterols in patients with sitosterolemia. Circulation 109: 966–971

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  • Spiekerkoetter U, Lindner M, Santer R et al. (2009) Treatment recommendations in long-chain fatty acid oxidation defects: consensus from a workshop. J Inherit Metab Dis 32: 498–505

    Article  CAS  PubMed  Google Scholar 

  • Winters JL (2011) Lipid apheresis, indications, and principles. J Clin Apher 26: 269–275

    Article  PubMed  Google Scholar 

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Koletzko, B. (2014). Störungen des Lipid- und Lipoproteinstoffwechsels. In: Reinhardt, D., Nicolai, T., Zimmer, KP. (eds) Therapie der Krankheiten im Kindes- und Jugendalter. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-41814-3_16

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  • DOI: https://doi.org/10.1007/978-3-642-41814-3_16

  • Publisher Name: Springer, Berlin, Heidelberg

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