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Asbestos Bodies and Non-asbestos Ferruginous Bodies

  • Victor L. RoggliEmail author
Chapter

Abstract

Asbestos bodies are the histologic hallmark of exposure to asbestos [1–4]. These structures are golden brown, beaded or segmented, dumbbell-shaped objects that have a characteristic microscopic appearance that is readily recognized by the pathologist. Their identification in histologic sections is an important component of the pathologic diagnosis of asbestosis (see  Chap. 4), and their presence serves to alert the pathologist that the patient has been exposed to airborne asbestos fibers. It is the purpose of this chapter to discuss the structure and development of asbestos bodies as well as their occurrence and distribution within human tissues. In addition, techniques for the quantification of asbestos bodies are reviewed, along with the relationship of asbestos body formation to the various types of asbestos fibers. Finally, the distinction of asbestos bodies from other ferruginous bodies based on light microscopic and analytical electron microscopic observations is emphasized. The identification and significance of asbestos bodies in cytologic specimens is discussed in  Chap. 9, and the relationship between asbestos body concentrations in pulmonary tissues and the various asbestos-associated diseases is reviewed in  Chap. 11.

Keywords

Lung Tissue Energy Dispersive Spectrometry Malignant Pleural Mesothelioma Asbestos Fiber Chrysotile Asbestos 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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© Springer-Verlag Berlin Heidelberg 2014

Authors and Affiliations

  1. 1.Department of PathologyDuke University Medical CenterDurhamUSA

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