Graphics-based Modeling

  • Ronald GieschkeEmail author
  • Daniel Serafin


Graphics greatly enhance the modeling of complex systems. As described in  Sect. 1.2, modeling generally starts with a drawing, or a model A, which connects relevant model elements in some logical order.


Command Line Custom View Integrator Block Simulation Viewer Gain Block 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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    The MathWorks (2012) SimBiology user’s guide (R2012b). The MathWorks, NatickGoogle Scholar
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    The MathWorks (2012) Simulink user’s guide (R2012b). The MathWorks, NatickGoogle Scholar
  3. 3.
    Pillai G, Gieschke R, Goggin T, Jacqmin P, Schimmer RC, Steimer JL (2004) A semimechanistic and mechanistic population PK-PD model for biomarker response to Ibandronate, a new biophosphonate for the treatment of osteoporosis. Brit J Clin Pharmacol 58:618–631CrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2014

Authors and Affiliations

  1. 1.Pharma Research and Early Development (pRED)F. Hoffmann-La Roche LtdBaselSwitzerland
  2. 2.F. Hoffmann-La Roche LtdBaselSwitzerland

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