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A Simple but Robust Complex Disease Classification Method Using Virtual Sample Template

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Part of the book series: Communications in Computer and Information Science ((CCIS,volume 375))

Abstract

With the advance of high throughput technologies, genomic or proteomic data are accumulated rapidly, demanding robust computational algorithms for large-scale biological data analysis and mining. In this work we propose a simple classification method based on virtual sample template (VST) and three distance measurements. Each VST corresponds to a subclass in training set. The label of a test sample is simply determined by measuring the similarity between the test sample and each VST using the three distance measurements. The test sample is assigned to the subclass of the VST with the minimum distance. Our experimental results indicate that the proposed method is robust in predicative performance. Compared with other common classification methods of complex disease, our method is simpler and often with improved classification performance.

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Wang, SL., Fang, Y., Fang, J. (2013). A Simple but Robust Complex Disease Classification Method Using Virtual Sample Template. In: Huang, DS., Gupta, P., Wang, L., Gromiha, M. (eds) Emerging Intelligent Computing Technology and Applications. ICIC 2013. Communications in Computer and Information Science, vol 375. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-39678-6_13

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  • DOI: https://doi.org/10.1007/978-3-642-39678-6_13

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-39677-9

  • Online ISBN: 978-3-642-39678-6

  • eBook Packages: Computer ScienceComputer Science (R0)

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