Basics of Bioinformatics

pp 69-100


Topics in Computational Genomics

  • Michael Q. ZhangAffiliated withDepartment of Molecular and Cell Biology, The University of Texas at DallasTsinghua National Laboratory for Information Science and Technology, Tsinghua University Email author 
  • , Andrew D. SmithAffiliated withCold Spring Harbor Laboratory

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Genomics began with large-scale sequencing of the human and many model organism genomes around 1990; rapid accumulation of vast genomic data brings a great challenge on how to decipher such massive molecular information. As bioinformatics in general, genome informatics is also data driven; many computational tools developed can soon be obsolete when new technologies and data types become available. Keeping this in mind if a student wants to work in this fascinating new field, one must be able to adapt quickly and to “shoot the moving targets” with the “just-in-time ammunition.”