Abstract
The following sections present the novel approach of combining continuous flow analysis (CFA) systems with the advantages of digital microfluidic (DMF) concepts. More precisely, the integration of electrostatic actuation into segmented flows (SF) is demonstrated. It is not focused on whether the actuation method should contingently be termed electrowetting rather than electrostatics, but in fact the intention is to show how well-known microfluidic concepts can be combined into an innovative and promising technique. The investigations show that a reasonable number of standard MEMS manufacturing processes are sufficient to fabricate the appropriate fluidic chips utilizing standard materials such as silicon and glass. The potentials emerging from the new systems are explicated, and a look ahead is given to possible applications as well as to research activities at issue.
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Acknowledgments
The presented work has been funded by the German Federal Ministry of Education and research under contract 16SV5058. The authors are much obliged to the following partners and colleagues for their respective contributions to success:
\(\bullet \) Boris Goj for the simulation in Maxwell and Yahia Cheriguen for his help with Comsol.
\(\bullet \) The Bioprocess Engineering Department of the Institute for Bioprocessing and Analytical Measurement Techniques in Heilbad Heiligenstadt, Germany, for support and numerous segmented flows;
\(\bullet \) Andrea Knauer and the Department Physical Chemistry and Microreaction Technology at the Ilmenau University of Technology, Germany;
\(\bullet \) Michael Bertko, Alexander Groß, Stefan Hampl, Lothar Dressler, Manuela Breiter, Tobias Remdt, Birgitt Hartmann, Gabriele Harnisch, David Vopel, Claudia Krauße, and Judith Wolf.
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Dittrich, L., Hoffmann, M. (2014). Chip-Integrated Solutions for Manipulation and Sorting of Micro Droplets and Fluid Segments by Electrical Actuation. In: Köhler, J., Cahill, B. (eds) Micro-Segmented Flow. Biological and Medical Physics, Biomedical Engineering. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-38780-7_4
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DOI: https://doi.org/10.1007/978-3-642-38780-7_4
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