Abstract
Melanotic macules are well-demarcated, fl at, pigmented lesions caused by a deposit of abundant melanin in the basal layer of the epidermis, accompanied by a slight or undetectable increase in the number of melanocytes. These deeply pigmented lesions contrast with those of actinic melanocytic hyperplasia in which no change in pigmentation or slight mottling is present. The lesions of lentigo simplex are smaller and histopathologically show a more signifi cant increase in the number of melanocytes.
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© 2014 Springer-Verlag Berlin Heidelberg
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Massi, G., LeBoit, P.E. (2014). Melanotic Macule. In: Histological Diagnosis of Nevi and Melanoma. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-37311-4_3
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DOI: https://doi.org/10.1007/978-3-642-37311-4_3
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Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-37310-7
Online ISBN: 978-3-642-37311-4
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