Physiology and Pathophysiology of Sneezing and Itching: Mechanisms of the Symptoms

  • Murat SonguEmail author
  • T. Metin Onerci


Sneeze is a coordinated protective respiratory reflex which arises due to stimulation of the upper respiratory tract, particularly the nasal cavity. Actually, activation of the central and peripheral nervous system plays a major role in the pathophysiology of this process. In fact, little is known about the sneeze reflex action, which sometimes becomes a sign associated to a series of different medical conditions. In this chapter, we aimed to review the physiology, pathophysiology, etiology, diagnosis, treatment, and complications of sneezing and itching.


Sneeze reflex Sneezing Itching Physiology Pathophysiology 


Conflict of Interest

The author has no financial relationship with a commercial entity that has an interest in the subject of this manuscript.


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Authors and Affiliations

  1. 1.Department of OtorhinolaryngologyIzmir Katip Celebi University Ataturk Research and Training HospitalIzmirTurkey
  2. 2.Department of Otorhinolaryngology, Faculty of MedicineHacettepe UniversityAnkaraTurkey

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