Zusammenfassung
Allergien und im speziellen hier atopieassoziierte Typ-I-Reaktionen sind klassische Umwelterkrankungen, wobei die auslösenden Substanzen (das sind die Allergene) großteils bereits charakterisiert und in rekombinanter Form erhältlich sind. Neben dieser Kausalkette, Allergen und Sensibilisierung gegenüber diesem Allergen, wirken Umwelteinflüsse unterschiedlichster Art modulierend – verstärkend oder protektiv – auf die Allergieentwicklung ein. Dabei muss zwischen biogenen und anthropogenen Umweltfaktoren unterschieden werden. Unter den allergiefördernden Faktoren kommt im Innenraum dem Tabakrauch, in der Außenluft der Exposition durch Verkehrsbelastung eine entscheidende Rolle zu. In der Außenluft bestehen Interaktionen zwischen den Allergenträgern (z. B. Pollen) und Luftschadstoffen, die u. U. zur weiteren Verstärkung allergischer Reaktionen, insbesondere in der Symptomverschlechterung, eine Rolle spielen. Durch den Klimawandel mit zunehmender globaler Erwärmung wird eine Veränderung der saisonalen Verteilung und weitere Häufung von allergischen Erkrankungen mit regional neuen bzw. veränderten Allergenen zu erwarten sein.
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Krämer, U., Buters, J., Ring, J., Behrendt, H. (2016). Allergie und Umwelt. In: Biedermann, T., Heppt, W., Renz, H., Röcken, M. (eds) Allergologie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-37203-2_40
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