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Kognitiv-mnestische Störungen bei multipler Sklerose

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Gedächtnisstörungen
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Zusammenfassung

Die multiple Sklerose (MS) ist eine der häufigsten neurologischen Erkrankungen des frühen und mittleren Erwachsenenalters. Ätiopathogenetisch wird die MS nach derzeitigem Kenntnisstand als autoimmunvermittelte Erkrankung des Zentralnervensystems angesehen, die zu multiplen, zeitlich und örtlich disseminierten Demyelinisierungen innerhalb des Zentralnervensystems führt. Pathoanatomisch findet sich neben der inflammatorischen Komponente auch ein neurodegenerativer Anteil. Der bei den meisten Erkrankungsfällen anfänglich schubförmige Krankheitsverlauf (schubförmige MS) kann in der weiteren Krankheitsevolution in einen chronisch-progredienten Verlauf übergehen. Neben einer Vielzahl von neurologischen Dysfunktionen können bereits im Frühstadium oder im Verlauf der MS verschiedene, neuropsychiatrische Störungen auftreten. Letztere sind entscheidend für den Arbeitsplatzerhalt und die Lebensqualität. Im Folgenden wird auf kognitive, insbesondere im Zusammenhang mit der Gedächtnisverarbeitung stehende Defizite eingegangen.

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Calabrese, P. (2013). Kognitiv-mnestische Störungen bei multipler Sklerose. In: Bartsch, T., Falkai, P. (eds) Gedächtnisstörungen. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-36993-3_12

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  • DOI: https://doi.org/10.1007/978-3-642-36993-3_12

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-36992-6

  • Online ISBN: 978-3-642-36993-3

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