Skip to main content

Gedächtnisstörungen im Kontext neurologisch-psychiatrischer Erkrankungen

  • Chapter
  • First Online:
Gedächtnisstörungen
  • 6658 Accesses

Zusammenfassung

Unser Gedächtnis ist ein Erinnerungsspeicher von Gelerntem und früher Erlebtem und ist als eine der komplexesten und wichtigsten kognitiven Fähigkeiten ein integraler Bestandteil des Menschen. „Gedächtnis“ ist hierbei ein Oberbegriff für eine Vielzahl zeitlich und inhaltlich unterschiedlicher Lern- und Erinnerungsleistungen mit dem Ziel, Informationen, sensorische Eindrücke und Emotionen innerhalb eines Verhaltenskontextes zu speichern und wieder abrufbar zu machen. Gedächtnisstörungen sind eine Störung der Fähigkeit, Informationen zu lernen, zu behalten oder abzurufen. Gedächtnisstörungen werden zumeist als Störungen des episodischen Gedächtnisses aufgefasst, welches besonders häufig bei neurologischen oder psychiatrischen Erkrankungen betroffen ist. Gedächtnisstörungen und kognitive Beeinträchtigungen bestimmen in besonderer Weise die funktionelle Leistungsfähigkeit im Rahmen neurologisch-psychiatrischer Erkrankungen.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 79.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Literatur

  • Alzheimer A (1907) Über eine eigenartige Erkrankung der Hirnrinde. Allgemeine Zeitschrift für Psychiatrie und Psychisch-gerichtliche Medizin 64: 146–148

    Google Scholar 

  • (Anonym) (2008) A network of memory clinics: when and how? Lancet Neurol 7(8): 663

    Article  Google Scholar 

  • Barak Y, Aizenberg D (2010) Is dementia preventable? Focus on Alzheimer’s disease. Expert Rev Neurother 10(11): 1689–1698

    Article  PubMed  Google Scholar 

  • Barnes DE, Santos-Modesitt W, Poelke G et al. (2013) The Mental Activity and eXercise (MAX) Trial: A Randomized Controlled Trial to Enhance Cognitive Function in Older Adults. JAMA 173(9):797–804

    Google Scholar 

  • Barnes DE, Yaffe K (2011) The projected effect of risk factor reduction on Alzheimer’s disease prevalence. Lancet Neurol 10(9): 819–828

    Article  PubMed Central  PubMed  Google Scholar 

  • Bartsch T (2012) The Hippocampus in the Clinical Neurosciences. The Clinical Neurobiology of the Hippocampus. T. Bartsch. Oxford, Oxford University Press: 1–10

    Chapter  Google Scholar 

  • Berger T, Song D, Chan R et al. (2012) Role of the hippocampus in memory formation: restorative encoding memory integration neural device as a cognitive neural prosthesis. IEEE Pulse 3(5): 17–22

    Article  PubMed  Google Scholar 

  • Cicerone KD, Langenbahn DM, Braden C, et al. (2011) Evidence-based cognitive rehabilitation: updated review of the literature from 2003 through 2008. Arch Phys Med Rehabil 92(4): 519–530

    Article  PubMed  Google Scholar 

  • Cramer SC, Sur M, Dobkin BH et al. (2011) Harnessing neuroplasticity for clinical applications. Brain 134(Pt 6): 1591–1609

    Article  PubMed Central  PubMed  Google Scholar 

  • Daviglus ML, Plassman BL, Pirzada A et al. (2011) Risk factors and preventive interventions for Alzheimer disease: state of the science. Arch Neurol 68(9): 1185–1190

    Article  PubMed  Google Scholar 

  • Deng W, Aimone JB, Gage FH (2010) New neurons and new memories: how does adult hippocampal neurogenesis affect learning and memory? Nat Rev Neurosci 11(5): 339–350

    Article  PubMed Central  PubMed  CAS  Google Scholar 

  • Deuschl G, Maier W (2009) S3 Leitlinie Demenzen, Deutsche Gesellschaft für Psychiatrie, Psychotherapie und Nervenheilkunde (DGPPN) & Deutsche Gesell­schaft für Neurologie (DGN). ▶ www.dggpp.de/documents/s3-leitlinie-demenz-kf.pdf

  • Erickson KI, Voss MW, Prakash RS et al. (2011) Exercise training increases size of hippocampus and improves memory. Proc Natl Acad Sci U S A 108(7): 3017–3022

    Article  PubMed Central  PubMed  Google Scholar 

  • Etgen T, Sander D, Bickel H, Forstl H (2011) Mild cognitive impairment and dementia: the importance of modifiable risk factors. Dtsch Arztebl Int 108(44): 743–750

    PubMed Central  PubMed  Google Scholar 

  • Fotuhi M, Do D, Jack C (2012) Modifiable factors that alter the size of the hippocampus with ageing. Nat Rev Neurol 8(4): 189–202

    PubMed  CAS  Google Scholar 

  • Frenguelli BG, Lynch G, Sahakian BJ et al. (2013) Cognitive enhancers: molecules, mechanisms and minds (Special issue). Neuropharmacology 64: 1

    Article  PubMed  CAS  Google Scholar 

  • Greely H, Sahakian B, Harris J et al. (2008) Towards responsible use of cognitive- enhancing drugs by the healthy. Nature 456(7223): 702–705

    Article  PubMed  CAS  Google Scholar 

  • Greenwood PM, Parasuraman R (2012) Nurturing the Older Brain and Mind. Cambridge, Massachusetts, USA, MIT Press

    Book  Google Scholar 

  • Hertzog C, Kramer A, Wilson R, Lindenberger U (2009) Enrichment effects on adult cognitive development : Can the functional capacity of older adults be preserved and enhanced ? Psychological Science in the Public Interest. 9: 1–65

    Article  Google Scholar 

  • Jagust W (2013) Vulnerable neural systems and the borderland of brain aging and neurodegeneration. Neuron 77(2): 219–234

    Article  PubMed Central  PubMed  CAS  Google Scholar 

  • Lautenschlager NT, Cox K, Cyarto EV (2012) The influence of exercise on brain aging and dementia. Biochim Biophys Acta 1822(3): 474–481

    Article  PubMed  CAS  Google Scholar 

  • Laxton AWT, Sankar A, Lozano M, Hamani C (2012) Deep brain stimulation effects on memory. J Neurosurg Sci 56(4): 341–344

    PubMed  CAS  Google Scholar 

  • Lazarov O, Mattson MP, Peterson DA et al. (2010) When neurogenesis encounters aging and disease. Trends Neurosci 33(12): 569–579

    Article  PubMed Central  PubMed  CAS  Google Scholar 

  • Merrill DA, Small GW (2011) Prevention in psychiatry: effects of healthy lifestyle on cognition. Psychiatr Clin North Am 34(1): 249–261

    Article  PubMed  Google Scholar 

  • Ngo HV, Martinetz T, Born J, Molle M (2013) Auditory Closed-Loop Stimulation of the Sleep Slow Oscillation Enhances Memory. Neuron

    Google Scholar 

  • NIMH (2012) Cognitive Training in Mental Disorders: Advancing the Science. Cognitive Training in Mental Disorders: Advancing the Science. April 09, 2012, Bethesda, Maryland, USA

    Google Scholar 

  • Pajonk FGT, Wobrock O, Gruber H et al. (2010) Hippocampal plasticity in response to exercise in schizophrenia. Arch Gen Psychiatry 67(2): 133–143

    Article  PubMed  Google Scholar 

  • Ranganath C, Flegal KE, Kelly LL (2011) Can cognitive training improve episodic memory? Neuron 72(5): 688–691

    Article  PubMed Central  PubMed  CAS  Google Scholar 

  • Robertson IH, Fitzpatrick SM (2008) The future of cognitive neurorehabilitation. In: Stuss DT, Winocur G, Robertson IH (eds) Cognitive Neurorehabilitation: Evidence and Application. Cambridge University Press, Cambridge, UK, pp 565–574

    Google Scholar 

  • Scarmeas N, Luchsinger JA, Schupf N et al. (2009) Physical activity, diet, and risk of Alzheimer disease. JAMA 302(6): 627–637

    Article  PubMed Central  PubMed  CAS  Google Scholar 

  • Scarmeas N, Stern Y (2004) Cognitive reserve: implications for diagnosis and prevention of Alzheimer’s disease. Current neurology and neuroscience reports 4(5): 374–380

    Article  PubMed Central  PubMed  Google Scholar 

  • Thöne-Otto A (2012) Diagnostik und Therapie von Gedächtnisstörungen. In: H. C. Diener et al. (Hrsg.), Leitlinien für Diagnostik und Therapie in der Neurologie (herausgegeben von der Kommission “Leitlinien” der Deutschen Gesellschaft für Neurologie. 5. Aufl., 1112–1132). Stuttgart: Thieme.

    Google Scholar 

  • Verghese J, Lipton RB, Katz MJ et al. (2003) Leisure activities and the risk of dementia in the elderly. N Engl J Med 348(25): 2508–2516

    Article  PubMed  Google Scholar 

  • Wallace TL, Ballard TM, Pouzet B, Riedel WJ, Wettstein JG (2011) Drug targets for cognitive enhancement in neuropsychiatric disorders. Pharmacol Biochem Behav 99(2): 130–145

    Article  PubMed  CAS  Google Scholar 

  • Williams JWPB, Burke J, Holsinger T, Benjamin S (2010) Preventing Alzheimer’s Disease and Cognitive Decline. D. Duke Evidence-based Practice Center, North Carolina. Rockville, MD, Agency for Healthcare Research and Quality. Evidence Reports/Technology Assessments, No. 193

    Google Scholar 

  • Wobrock T, Hasan A, Falkai P (2012) Innovative treatment approaches in schizophrenia enhancing neuroplasticity: aerobic exercise, erythropoetin and repetitive transcranial magnetic stimulation. Curr Pharm Biotechnol 13(8): 1595–1605

    Article  PubMed  CAS  Google Scholar 

  • Woods BE, Aguirre AE, Spector M (2012) Cognitive stimulation to improve cognitive functioning in people with dementia. Cochrane Database Syst Rev 2: CD005562

    Google Scholar 

  • Wykes T, Huddy V, Cellard C et al. (2011) A meta-analysis of cognitive remediation for schizophrenia: methodology and effect sizes. Am J Psychiatry 168(5): 472–485

    Article  PubMed  Google Scholar 

  • Zimerman MM, Nitsch P, Giraux C et al. (2013) Neuroenhancement of the aging brain: restoring skill acquisition in old subjects. Ann Neurol 73(1): 10–15

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2013 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Bartsch, T., Falkai, P. (2013). Gedächtnisstörungen im Kontext neurologisch-psychiatrischer Erkrankungen. In: Bartsch, T., Falkai, P. (eds) Gedächtnisstörungen. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-36993-3_1

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-36993-3_1

  • Published:

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-36992-6

  • Online ISBN: 978-3-642-36993-3

  • eBook Packages: Medicine (German Language)

Publish with us

Policies and ethics