Plasma Fatty Acid Profiles During the First Year in Dogs with and without Hip Dysplasia: Preliminary Results
- 931 Downloads
At the Military Veterinary Center of Grossetto, where operative dogs from the Italian Army are raised and trained, more than 70 % of the discharges for unfitness are due to articular pathologies like hip and elbow dysplasia. The aim of this study was to investigate fatty acid metabolism of dogs during the growth phase, and its modulation by a fish-based diet. Only 2 out of the 32 subjects were affected by articular pathologies during the study. Still, both subjects had lower levels of arachidonic acid and higher levels of docosahexaenoic acid. Moreover, we observed that the ratio of eicosapentaenoic to docosahexaenoic acids, an indicator of delta-6 desaturase activity, drops dramatically during the first year in the German shepherd.
KeywordsDog Dysplasia Fatty acids
This research was supported by the Italian “Ministero della difesa,” grant name: “Ricerca sull’incidenza dell’artrosi nel cane militare e strategia di prevenzione e controllo”.
- Renaville B, Mullen A, Moloney F, Larondelle Y, Schneider YJ, Roche HM (2006) Eicosapentaenoic acid and 3, 10 dithia stearic acid inhibit the desaturation of trans-vaccenic acid into cis-9, trans-11-conjugated linoleic acid through different pathways in Caco-2 and T84 cells. Br J Nutr 95:688–695PubMedCrossRefGoogle Scholar
- Roush JK, Cross AR, Renberg WC, Dodd CE, Sixby KA, Fritsch DA, Allen TA, Jewell DE, Richardson DC, Leventhal PS, Hahn KA (2010) Evaluation of the effects of dietary supplementation with fish oil omega-3 fatty acids on weight bearing in dogs with osteoarthritis. J Am Vet Med Assoc 236:67–73PubMedCrossRefGoogle Scholar
- SAS Institute Inc. (2010) SAS/IML ® 9.22 User’s Guide. Cary, NC: SAS Institute Inc.Google Scholar
- Walters J, Hockett T, Ogilvie G, Fettman M (2010) Polyunsaturated Fatty Acid dietary supplementation induces lipid peroxidation in normal dogs. Vet Med Int, 2010 Article ID 619083, 4 pages. doi: 10.4061/2010/619083
- Willis M (1989) Hip dysplasia. In: Willis MB (ed) Genetics of the dog. Howell Book House, New York, pp 144–179Google Scholar