Nomenclature
EC number
1.1.1.300
Systematic name
retinol:NADP+ oxidoreductase
Recommended name
NADP-retinol dehydrogenase
Synonyms
CG2065 <22> [22]
CG2070 <21> [22]
CG30491 <23> [22]
CG3842 <24> [22]
NADP(H)-dependent retinol dehydrogenase/reductase <16,17,18,19> [17]
NADP+-dependent all-trans-retinol dehydrogenase <2> [23]
NDRD <15> [14]
NRDR <16,17,18,19> [17]
NRDRA1 <19> (<19> alternatively spliced variant with a complete deletion of exons 3-6 [17]) [17]
NRDRB1 <17> (<17> alternatively spliced variant with a complete deletion of exon 3 [17]) [17]
NRDRB2 <18> (<18> alternatively spliced variant with a complete deletion of exons 3 and 6 [17]) [17]
RDH <5> [13]
RDH10 <2> [23]
RDH11 <2,9,11> [4,7,18,23]
RDH12 <1,2,7,12> [4,8,10,12,18,20,23]
RDH13 <20> [16]
RDH14 <8> [4,10]
RDH5 <10> [10]
RHD8 <2> [24]
RalR1 <2> [2,3]
Retinol dehydrogenase <1,5> [12,13]
all-trans retinal reductase <15> [14]
all-trans-retinol dehydrogenase <2> [1]
hRDH5 <11> [10]
hRoDH <2> [5]
mRDH11 <9> [10]
mouse RDH11 <9> [10]
peroxisomal NADP(H)-dependent retinol dehydrogenase-reductase <15> [14]
photoreceptor retinol dehydrogenase <2> [24]
photoreceptor-associated retinol dehydrogenase <6,14> [26]
photoreceptor-specific retinol dehydrogenase <1> [9]
prRDH <1,6,14> [9,26]
retSDR1 <2,13> [10]
retinal reductase <2,15> [14,23]
retinal reductase 1 <2> [2,3]
retinol dehydrogenase 12 <7> [8]
retinol dehydrogenase 13 <20> [16]
retinol dehydrogenase [NADP+] <15> [14]
short-chain dehydrogenase/reductase RRD <1> [21]
Additional information <16,17,18,19> (<16,17,18,19> enzyme additionally displays high aldehyde reductase activity in retinoic acid metabolism [17]) [17]
CAS registry number
90033-53-8 (cf. EC 1.1.1.105)
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References
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Schomburg, D., Schomburg, I. (2013). NADP-retinol dehydrogenase 1.1.1.300. In: Schomburg, D., Schomburg, I. (eds) Class 1 Oxidoreductases. Springer Handbook of Enzymes. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-36265-1_6
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