Nomenclature
EC number
1.3.1.85
Systematic name
(2S)-ethylmalonyl-CoA:NADP+ oxidoreductase (decarboxylating)
Recommended name
crotonyl-CoA carboxylase/reductase
Synonyms
CCR <1> [3]
crotonyl-CoA reductase (carboxylating)
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References
Erb, T.J.; Berg, I.A.; Brecht, V.; Mueller, M.; Fuchs, G.; Alber, B.E.: Synthesis of C5-dicarboxylic acids from C2-units involving crotonyl-CoA carboxylase/reductase: the ethylmalonyl-CoA pathway. Proc. Natl. Acad. Sci. USA, 104, 10631-10636 (2007)
Alber, B.E.: Biotechnological potential of the ethylmalonyl-CoA pathway. Appl. Microbiol. Biotechnol., 89, 17-25 (2010)
Erb, T.J.; Brecht, V.; Fuchs, G.; Muller, M.; Alber, B.E.: Carboxylation mechanism and stereochemistry of crotonyl-CoA carboxylase/reductase, a carboxylating enoyl-thioester reductase. Proc. Natl. Acad. Sci. USA, 106, 8871-8876 (2009)
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Schomburg, D., Schomburg, I. (2013). crotonyl-CoA carboxylase/reductase 1.3.1.85. In: Schomburg, D., Schomburg, I. (eds) Class 1 Oxidoreductases. Springer Handbook of Enzymes. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-36265-1_43
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