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16S rRNA (guanine966-N2)-methyltransferase 2.1.1.171

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Book cover Class 2–3.2 Transferases, Hydrolases

Part of the book series: Springer Handbook of Enzymes ((HDBKENZYMES))

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Nomenclature

EC number

 2.1.1.171

Systematic name

 S-adenosyl-l-methionine:16S rRNA (guanine966-N2)-methyltransferase

Recommended name

 16S rRNA (guanine966-N2)-methyltransferase

Synonyms

 16S rRNA-specific methyltransferases m2GMT <1> [4]

 RNA:(guanine-N2) methyltransferase RsmD <1> [3]

 RsmD <1> (<1> gene name [1,2]) [1,2]

 m2G966 methyltransferase <1> [1,4]

 yhhF <1> (<1> gene name [1,2]) [1,2]

CAS registry number

 50812-26-5

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References

  1. Lesnyak, D.V.; Osipiuk, J.; Skarina, T.; Sergiev, P.V.; Bogdanov, A.A.; Edwards, A.; Savchenko, A.; Joachimiak, A.; Dontsova, O.A.: Methyltransferase that modifies guanine 966 of the 16 S rRNA: functional identification and tertiary structure. J. Biol. Chem., 282, 5880-5887 (2007)

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  2. Sergiev, P.V.; Bogdanov, A.A.; Dontsova, O.A.: Ribosomal RNA guanine-(N2)- methyltransferases and their targets. Nucleic Acids Res., 35, 2295-2301 (2007)

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  3. Bujnicki, J.M.: Rychlewski. L.: RNA:(guanine-(N2)) methyltransferases RsmC/ RsmD and their homologs revisited–bioinformatic analysis and prediction of the active site based on the uncharacterized Mj0882 protein structure. BMC Bioinformatics, 3, 0000 (2002)

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  4. Weitzmann, C.; Tumminia, S.J.; Boublik, M.; Ofengand, J.: A paradigm for local conformational control of function in the ribosome: binding of ribosomal protein S19 to Escherichia coli 16S rRNA in the presence of 57 is required for methylation of m2G966 and blocks methylation of m C967 by their respective methyltransferases. Nucleic Acids Res., 19, 7089-7095 (1991)

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Correspondence to Dietmar Schomburg .

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Schomburg, D., Schomburg, I. (2013). 16S rRNA (guanine966-N2)-methyltransferase 2.1.1.171. In: Schomburg, D., Schomburg, I. (eds) Class 2–3.2 Transferases, Hydrolases. Springer Handbook of Enzymes. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-36240-8_9

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