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Noninfectious Arthritis

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Geriatric Imaging

Abstract

Noninfectious arthritis is among the most common musculoskeletal problems affecting the elderly. The resulting loss of mobility and physical independence can be particularly devastating. The clinical and radiological presentation of late-onset arthritis may differ significantly from the early-onset form. Conversely, long-lasting arthritis which began several decades earlier may be associated with particular complications. The aim of this chapter is to present the most frequent forms of noninfectious arthritis of the elderly: rheumatoid arthritis, spondyloarthritis, gout, and calcium pyrophosphate dihydrate deposition disease.

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Abbreviations

AS:

Ankylosing spondylitis

CPPD:

Calcium pyrophosphate dihydrate deposition

DISH:

Diffuse idiopathic skeletal hyperostosis

ESR:

Erythrocyte sedimentation rate

MCP:

Metacarpophalangeal joints

MTP:

Metatarsophalangeal joints

OA:

Osteoarthritis

PA:

Psoriatic arthritis

PIP:

Proximal interphalangeal joints

PMR:

Polymyalgia rheumatica

RA:

Rheumatoid arthritis

RS3PE:

Remitting seronegative symmetrical synovitis with pitting edema syndrome

STIR:

Short tau inversion sequence

References

  • Aggarwal A, Misra R, Chandrasekhar S, Prasad KN, Dayal R, Ayyagari A (1997) Is undifferentiated seronegative spondyloarthropathy a forme fruste of reactive arthritis? Br J Rheumatol 36(9):1001–1004

    Article  PubMed  CAS  Google Scholar 

  • Aletaha D, Neogi T, Silman AJ, Funovits J, Felson DT, Bingham CO 3rd, Birnbaum NS, Burmester GR, Bykerk VP et al (2010) 2010 rheumatoid arthritis classification criteria: an American College of Rheumatology/European League against rheumatism collaborative initiative. Ann Rheum Dis 69(9):1580–1588

    Article  PubMed  Google Scholar 

  • Backhaus M, Burmester GR, Sandrock D, Loreck D, Hess D, Scholz A, Blind S, Hamm B, Bollow M (2002) Prospective two year follow up study comparing novel and conventional imaging procedures in patients with arthritic finger joints. Ann Rheum Dis 61(10):895–904

    Article  PubMed  CAS  Google Scholar 

  • Barozzi L, Olivieri I, De Matteis M, Padula A, Pavlica P (1998) Seronegative spondylarthropathies: imaging of spondylitis, enthesitis and dactylitis. Eur J Radiol 27(Suppl 1):S12–S17

    Article  PubMed  Google Scholar 

  • Bhansing KJ, van Bon L, Janssen M, Radstake TRDJ (2010) Gout: a clinical syndrome illustrated and discussed. Neth J Med 68(9):352–359

    PubMed  CAS  Google Scholar 

  • Bloch C, Hermann G, Yu TF (1980) A radiologic reevaluation of gout: a study of 2,000 patients. AJR Am J Roentgenol 134(4):781–787

    Article  PubMed  CAS  Google Scholar 

  • Boutry N, Lardé A, Demondion X, Flipo RM, van Holsbeeck M, Cotten A (2003) Value of US imaging of metacarpophalangeal joints in patients with early rheumatoid arthritis. J Radiol 84(6):659–665

    PubMed  CAS  Google Scholar 

  • Braun J, van der Heijde D (2002) Imaging and scoring in ankylosing spondylitis. Best Pract Res Clin Rheumatol 16(4):573–604

    PubMed  CAS  Google Scholar 

  • Breuer GS, Nesher G (2012) What does imaging tell us about polymyalgia rheumatica? Rheumatology (Oxford) 51:5–6, Epub 2011 Jul 6

    Article  Google Scholar 

  • Calvo-Alén J, Corrales A, Sánchez-Andrada S, Fernández-Echevarría MA, Peña JL, Rodríguez-Valverde V (2005) Outcome of late-onset rheumatoid arthritis. Clin Rheumatol 24(5):485–489

    Article  PubMed  Google Scholar 

  • Campagna R, Pessis E, Feydy A, Guerini H, Thévenin F, Chevrot A, Drapé J-L (2009) Fractures of the ankylosed spine: MDCT and MRI with emphasis on individual anatomic spinal structures. AJR Am J Roentgenol 192(4):987–995

    Article  PubMed  Google Scholar 

  • Canella C, Philippe P, Pansini V, Salleron J, Flipo R-M, Cotten A (2011) Use of tomosynthesis for erosion evaluation in rheumatoid arthritic hands and wrists. Radiology 258(1):199–205

    Article  PubMed  Google Scholar 

  • Caplanne D, Tubach F, Le Parc JM (1997) Late onset spondylarthropathy: clinical and biological comparison with early onset patients. Ann Rheum Dis 56(3):176–179

    Article  PubMed  CAS  Google Scholar 

  • Caporali R, Montecucco C, Epis O, Bobbio-Pallavicini F, Maio T, Cimmino MA (2001) Presenting features of polymyalgia rheumatica (PMR) and rheumatoid arthritis with PMR-like onset: a prospective study. Ann Rheum Dis 60(11):1021–1024

    Article  PubMed  CAS  Google Scholar 

  • Coates LC, Cook R, Lee K-A, Chandran V, Gladman DD (2010) Frequency, predictors, and prognosis of sustained minimal disease activity in an observational psoriatic arthritis cohort. Arthritis Care Res (Hoboken) 62(7):970–976

    Article  Google Scholar 

  • De Leonardis F, Govoni M, Colina M, Bruschi M, Trotta F (2007) Elderly-onset gout: a review. Rheumatol Int 28(1):1–6

    Article  PubMed  Google Scholar 

  • Denis A, Lapegue F, Sans N, Vial J, Chiavassa-Gandois H, Fournie B, Railhac JJ (2010) Cross-sectional imaging of peripheral involvement in psoriatic arthritis. J Radiol 91(1 Pt 2):126–139

    Article  PubMed  CAS  Google Scholar 

  • Dieppe PA (1991) Investigation and management of gout in the young and the elderly. Ann Rheum Dis 50(4):263–266

    Article  PubMed  CAS  Google Scholar 

  • Dieppe PA, Alexander GJ, Jones HE, Doherty M, Scott DG, Manhire A, Watt I (1982) Pyrophosphate arthropathy: a clinical and radiological study of 105 cases. Ann Rheum Dis 41(4):371–376

    Article  PubMed  CAS  Google Scholar 

  • Doita M, Shimomura T, Maeno K, Nishida K, Fujioka H, Kurosaka M (2007) Calcium pyrophosphate dihydrate deposition in the transverse ligament of the atlas: an unusual cause of cervical myelopathy. Skeletal Radiol 36(7):699–702

    Article  PubMed  CAS  Google Scholar 

  • El Maghraoui A (2004) Osteoporosis and ankylosing spondylitis. Joint Bone Spine 71(4):291–295

    Article  PubMed  Google Scholar 

  • El-Labban AS, Omar HASA, El-Shereif RR, Ali F, El-Mansoury TM (2010) Pattern of young and old onset rheumatoid arthritis (YORA and EORA) among a group of Egyptian patients with rheumatoid arthritis. Clin Med Insights Arthritis Musculoskelet Disord 3:25–31

    Article  PubMed  Google Scholar 

  • Feldtkeller E, Khan MA, van der Heijde D, van der Linden S, Braun J (2003) Age at disease onset and diagnosis delay in HLA-B27 negative vs. positive patients with ankylosing spondylitis. Rheumatol Int 23(2):61–66

    PubMed  Google Scholar 

  • Gavet F, Tournadre A, Soubrier M, Ristori JM, Dubost JJ (2005) Septic arthritis in patients aged 80 and older: a comparison with younger adults. J Am Geriatr Soc 53(7):1210–1213

    Article  PubMed  Google Scholar 

  • Gladman DD, Antoni C, Mease P, Clegg DO, Nash P (2005) Psoriatic arthritis: epidemiology, clinical features, course, and outcome. Ann Rheum Dis 64(Suppl 2):ii14–ii17

    Article  PubMed  Google Scholar 

  • Gonzalez-Gay MA, Hajeer AH, Dababneh A, Makki R, Garcia-Porrua C, Thomson W, Ollier W (2001) Seronegative rheumatoid arthritis in elderly and polymyalgia rheumatica have similar patterns of HLA association. J Rheumatol 28(1):122–125

    PubMed  CAS  Google Scholar 

  • Grahame R (1976) The problems of diagnosis of arthritis in the elderly. Proc R Soc Med 69(12):926–928

    PubMed  CAS  Google Scholar 

  • Gutierrez M, Filippucci E, Salaffi F, Grassi W (2009) The current role of ultrasound in the assessment of crystal-related arthropathies. Reumatismo 61(3):216–221

    PubMed  CAS  Google Scholar 

  • Halla JT, Fallahi S, Hardin JG (1986) Small joint involvement: a systematic roentgenographic study in rheumatoid arthritis. Ann Rheum Dis 45(4):327–330

    Article  PubMed  CAS  Google Scholar 

  • Häntzschel H, Bird HA, Seidel W, Krüger W, Neumann G, Schneider G, Wright V (1991) Polymyalgia rheumatica and rheumatoid arthritis of the elderly: a clinical, laboratory, and scintigraphic comparison. Ann Rheum Dis 50(9):619–622

    Article  PubMed  Google Scholar 

  • Helmick CG, Felson DT, Lawrence RC, Gabriel S, Hirsch R, Kwoh CK, Liang MH, Kremers HM, Mayes MD et al (2008) Estimates of the prevalence of arthritis and other rheumatic conditions in the United States. Part I. Arthritis Rheum 58(1):15–25

    Article  PubMed  Google Scholar 

  • Jacobson JA, Girish G, Jiang Y, Resnick D (2008a) Radiographic evaluation of arthritis: inflammatory conditions. Radiology 248(2):378–389

    Article  PubMed  Google Scholar 

  • Jacobson JA, Girish G, Jiang Y, Sabb BJ (2008b) Radiographic evaluation of arthritis: degenerative joint disease and variations. Radiology 248(3):737–747

    Article  PubMed  Google Scholar 

  • Kaipiainen-Seppänen O (1996) Incidence of psoriatic arthritis in Finland. Br J Rheumatol 35(12):1289–1291

    Article  PubMed  Google Scholar 

  • Kavanaugh AF (1997) Rheumatoid arthritis in the elderly: is it a different disease? Am J Med 103(6A):40S–48S

    Article  PubMed  CAS  Google Scholar 

  • Kim SY, Schneeweiss S, Liu J, Daniel GW, Chang C-L, Garneau K, Solomon DH (2010) Risk of osteoporotic fracture in a large population-based cohort of patients with rheumatoid arthritis. Arthritis Res Ther 12(4):R154

    Article  PubMed  Google Scholar 

  • Koivikko MP, Koskinen SK (2008) MRI of cervical spine injuries complicating ankylosing spondylitis. Skeletal Radiol 37(9):813–819

    Article  PubMed  Google Scholar 

  • Kotil K, Yavasca P (2007) Lumbar radiculopathy in ankylosing spondylitis with dural ectasia. J Clin Neurosci 14(10):981–983

    Article  PubMed  Google Scholar 

  • Kroft LJM, Reijnierse M, Kloppenburg M, Verbist BM, Bloem JL, van Buchem MA (2004) Rheumatoid arthritis: epidural enhancement as an underestimated cause of subaxial cervical spinal stenosis. Radiology 231(1):57–63

    Article  PubMed  Google Scholar 

  • López-Montilla MD, González J, Martínez FG, Fernández-Moreno JR, Collantes E (2002) Clinical features of late onset psoriatic arthritis. Exp Gerontol 37(2–3):441–443

    Article  PubMed  Google Scholar 

  • Mavragani CP, Moutsopoulos HM (1999) Rheumatoid arthritis in the elderly. Exp Gerontol 34(3):463–471

    Article  PubMed  CAS  Google Scholar 

  • McGonagle D, Marzo-Ortega H, O’Connor P, Gibbon W, Hawkey P, Henshaw K, Emery P (2002) Histological assessment of the early enthesitis lesion in spondyloarthropathy. Ann Rheum Dis 61(6):534–537

    Article  PubMed  CAS  Google Scholar 

  • Michel JL, Souteyrand AC, Kabre M, Dubost JJ, Soubrier M, Ristori JM (2007) Fractures of the ankylosed spine: MRI features. J Radiol 88(11 Pt 1):1703–1706

    Article  PubMed  CAS  Google Scholar 

  • Michet CJ Jr, Evans JM, Fleming KC, O’Duffy JD, Jurisson ML, Hunder GG (1995) Common rheumatologic diseases in elderly patients. Mayo Clin Proc 70(12):1205–1214

    Article  PubMed  Google Scholar 

  • Miquel A, Pradel C, Jomaah N, Bienvenot P, Menu Y (2010) Cross-sectional imaging of peripheral involvement in ankylosing spondylitis. J Radiol 91(1 Pt 2):151–161

    Article  PubMed  CAS  Google Scholar 

  • Narváez JA, Narváez J, De Lama E, De Albert M (2010) MR imaging of early rheumatoid arthritis. Radiographics 30(1):143–163; discussion 163–165

    Article  PubMed  Google Scholar 

  • Neogi T (2011) Clinical practice. Gout N Engl J Med 364(5):443–452

    Article  CAS  Google Scholar 

  • Olivieri I, D’Angelo S, Cutro MS, Padula A, Peruz G, Montaruli M, Scarano E, Giasi V, Palazzi C et al (2007a) Diffuse idiopathic skeletal hyperostosis may give the typical postural abnormalities of advanced ankylosing spondylitis. Rheumatology (Oxford) 46(11):1709–1711

    Article  CAS  Google Scholar 

  • Olivieri I, Garcia-Porrua C, Padula A, Cantini F, Salvarani C, Gonzalez-Gay MA (2007b) Late onset undifferentiated spondyloarthritis presenting with polymyalgia rheumatica features: description of seven cases. Rheumatol Int 27(10):927–933

    Article  PubMed  Google Scholar 

  • Olivieri I, Pipitone N, D’ Angelo S, Padula A, Salvarani C (2009) Late-onset rheumatoid arthritis and late-onset spondyloarthritis. Clin Exp Rheumatol 27(4 Suppl 55):S139–S145

    PubMed  CAS  Google Scholar 

  • Østergaard M, Pedersen SJ, Døhn UM (2008) Imaging in rheumatoid arthritis–status and recent advances for magnetic resonance imaging, ultrasonography, computed tomography and conventional radiography. Best Pract Res Clin Rheumatol 22(6):1019–1044

    Article  PubMed  Google Scholar 

  • Perez-Ruiz F, Dalbeth N, Urresola A, de Miguel E, Schlesinger N (2009) Imaging of gout: findings and utility. Arthritis Res Ther 11(3):232

    Article  PubMed  Google Scholar 

  • Punzi L, Pianon M, Rossini P, Schiavon F, Gambari PF (1999) Clinical and laboratory manifestations of elderly onset psoriatic arthritis: a comparison with younger onset disease. Ann Rheum Dis 58(4):226–229

    Article  PubMed  CAS  Google Scholar 

  • Pye SR, Adams JE, Ward KA, Bunn DK, Symmons DPM, O’Neill TW (2010) Disease activity and severity in early inflammatory arthritis predict hand cortical bone loss. Rheumatology (Oxford) 49(10):1943–1948

    Article  Google Scholar 

  • Resnick D, Cone R (1984) Pathological fractures in rheumatoid arthritis. Radiographics 4(3):549–562

    Google Scholar 

  • Resnick D, Niwayama G, Goergen TG, Utsinger PD, Shapiro RF, Haselwood DH, Wiesner KB (1977) Clinical, radiographic and pathologic abnormalities in calcium pyrophosphate dihydrate deposition disease (CPPD): pseudogout. Radiology 122(1):1–15

    PubMed  CAS  Google Scholar 

  • Salam A, Henry R, Sheeran T (2008) Acute onset polyarthritis in older people: is it RS3PE syndrome? Cases J 1(1):132

    Article  PubMed  Google Scholar 

  • Schlesinger N (2005) Diagnosis of gout: clinical, laboratory, and radiologic findings. Am J Manag Care 11(15 Suppl):S443–S450; quiz S465–S468

    PubMed  Google Scholar 

  • Sebes JI, Nasrallah NS, Rabinowitz JG, Masi AT (1978) The relationship between HLA-B27 positive peripheral arthritis and sacroiliitis. Radiology 126(2):299–302

    PubMed  CAS  Google Scholar 

  • Sommer OJ, Kladosek A, Weiler V, Czembirek H, Boeck M, Stiskal M (2005) Rheumatoid arthritis: a practical guide to state-of-the-art imaging, image interpretation, and clinical implications. Radiographics 25(2):381–398

    Article  PubMed  Google Scholar 

  • Steinbach LS, Resnick D (1996) Calcium pyrophosphate dihydrate crystal deposition disease revisited. Radiology 200(1):1–9

    PubMed  CAS  Google Scholar 

  • Szekanecz Z, Szekanecz E, Bakó G, Shoenfeld Y (2011) Malignancies in autoimmune rheumatic diseases – a mini-review. Gerontology 57(1):3–10

    Article  PubMed  Google Scholar 

  • Taljanovic MS, Hunter TB, Wisneski RJ, Seeger JF, Friend CJ, Schwartz SA, Rogers LF (2009) Imaging characteristics of diffuse idiopathic skeletal hyperostosis with an emphasis on acute spinal fractures: review. AJR Am J Roentgenol 193(3 Suppl):S10–S19, Quiz S20–S24

    Article  PubMed  Google Scholar 

  • ter Borg EJ, Rasker JJ (1987) Gout in the elderly, a separate entity? Ann Rheum Dis 46(1):72–76

    Article  PubMed  Google Scholar 

  • Thiele RG, Schlesinger N (2007) Diagnosis of gout by ultrasound. Rheumatology (Oxford) 46(7):1116–1121

    Article  CAS  Google Scholar 

  • Turkcapar N, Demir O, Atli T, Kopuk M, Turgay M, Kinikli G, Duman M (2006) Late onset rheumatoid arthritis: clinical and laboratory comparisons with younger onset patients. Arch Gerontol Geriatr 42(2):225–231

    Article  PubMed  Google Scholar 

  • Van Hoydonck M, de Vlam K, Westhovens R, Luyten FP, Lories RJ (2010) Destructive dural ectasia of dorsal and lumbar spine with cauda equina syndrome in a patient with ankylosing spondylitis. Open Rheumatol J 4:31–34

    Article  PubMed  Google Scholar 

  • van Staa TP, Geusens P, Bijlsma JWJ, Leufkens HGM, Cooper C (2006) Clinical assessment of the long-term risk of fracture in patients with rheumatoid arthritis. Arthritis Rheum 54(10):3104–3112

    Article  PubMed  Google Scholar 

  • Westerveld LA, Verlaan JJ, Oner FC (2009) Spinal fractures in patients with ankylosing spinal disorders: a systematic review of the literature on treatment, neurological status and complications. Eur Spine J 18(2):145–156

    Article  PubMed  CAS  Google Scholar 

  • Wolfe BK, O’Keeffe D, Mitchell DM, Tchang SP (1987) Rheumatoid arthritis of the cervical spine: early and progressive radiographic features. Radiology 165(1):145–148

    PubMed  CAS  Google Scholar 

  • Zhang W, Doherty M, Pascual E, Bardin T, Barskova V, Conaghan P, Gerster J, Jacobs J, Leeb B et al (2006) EULAR evidence based recommendations for gout. Part I: diagnosis. Report of a task force of the standing committee for international clinical studies including therapeutics (ESCISIT). Ann Rheum Dis 65(10):1301–1311

    Article  PubMed  CAS  Google Scholar 

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Gheno, R., Pansini, V., Rosca, C.E., Flipo, RM., Cotten, A. (2013). Noninfectious Arthritis. In: Guglielmi, G., Peh, W., Guermazi, A. (eds) Geriatric Imaging. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-35579-0_6

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